Early-onset parkinsonism (EO parkinsonism), defined as subjects with disease onset before
the age of 40 or 50 years, can be the main clinical presentation of a variety of conditions that …

Young onset Parkinson's disease patients, typically aged 21 to between 40 and 55, have
symptomatology similar to regular onset patients. Despite this, we suspect that physicians …

Cardinal motor features of Parkinson's disease (PD) appear when about half of the nigral
dopamine neurons have disappeared. Based on extrapolations from post-mortem and …

ABSTRACT Background Early‐onset Parkinson's disease (EOPD)/young‐onset Parkinson's
disease (YOPD) is defined as Parkinson's disease (PD) with an age at onset (AAO) after age …

Juvenile parkinsonism, with onset prior to age 21 years, is a relatively rare syndrome. It is
caused by a group of heterogeneous entities that can present with a clinical picture similar to …

Background Increasing evidence suggests that early-onset Parkinson's disease (EOPD) is
heterogeneous in its clinical presentation and progression. Defining subtypes of EOPD is …

Parkinson disease (PD) is characterized by a wide variety of motor and nonmotor symptoms.
Although recently nonmotor symptoms have gained considerable relevance and interest …

Therapeutic options for Parkinson's disease (PD) are currently limited to symptomatic
agents. Levodopa is the most efficacious treatment; however, higher doses and long-term …

[Frontiers in Bioscience 8, s568-578, May 1, 2003] 568 EARLY ONSET PARKINSONISM Oscar
S. Gershanik Sección Enfermedades Extrapi Page 1 [Frontiers in Bioscience 8, s568-578, May …

In people with young onset Parkinson's disease (YOPD), onset of symptoms is between 21
and 40 years of age. The distinction between YOPD and late-onset Parkinson's disease is …