To date, most expression quantitative trait loci (eQTL) studies, which investigate how genetic
variants contribute to gene expression, have been performed in heterogeneous brain …

Genome-wide association studies have nominated many genetic variants for common
human traits, including diseases, but in many cases the underlying biological reason for a …

Identification of therapeutic targets from genome-wide association studies (GWAS) requires
insights into downstream functional consequences. We harmonized 8,613 RNA-sequencing …

Germ-line genetic control of gene expression occurs via expression quantitative trait loci
(eQTLs). We present a large, exon-specific eQTL data set covering ten human brain regions …

Interpretation of the function of non-coding risk loci for neuropsychiatric disorders and brain-
relevant traits via gene expression and alternative splicing quantitative trait locus (e/sQTL) …

Current catalogs of brain expression quantitative trait loci (eQTL) are incomplete and the
findings do not replicate well across studies. All existing cortical eQTL studies are small and …

While large-scale, genome-wide association studies (GWAS) have identified hundreds of
loci associated with brain-related traits, identification of the variants, genes and molecular …

Genetic variants that modify brain gene expression may also influence risk for human
diseases. We measured expression levels of 24,526 transcripts in brain samples from the …

There is increasing evidence that many risk loci found using genome-wide association
studies are molecular quantitative trait loci (QTLs). Here we introduce a new set of functional …

Genetic influences on gene expression in the human fetal brain plausibly impact upon a
variety of postnatal brain-related traits, including susceptibility to neuropsychiatric disorders …