Characterization of a neutralizing antibody that recognizes a loop region adjacent to the receptor-binding interface of the SARS-CoV-2 spike receptor-binding domain
I Anzai, J Fujita, C Ono, Y Kosaka… - Microbiology …, 2024 - Am Soc Microbiol
Although the global crisis caused by the coronavirus disease 2019 (COVID-19) pandemic is
over, the global epidemic of the disease continues. Severe acute respiratory syndrome …
over, the global epidemic of the disease continues. Severe acute respiratory syndrome …
Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies
C Yi, X Sun, J Ye, L Ding, M Liu, Z Yang, X Lu… - Cellular & molecular …, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by the novel human coronavirus
SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein …
SARS-CoV-2, is currently a major threat to public health worldwide. The viral spike protein …
Structural basis of a human neutralizing antibody specific to the SARS-CoV-2 spike protein receptor-binding domain
M Yang, J Li, Z Huang, H Li, Y Wang, X Wang… - Microbiology …, 2021 - Am Soc Microbiol
The emerging new lineages of severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) have marked a new phase of coronavirus disease 2019 (COVID-19). Understanding …
CoV-2) have marked a new phase of coronavirus disease 2019 (COVID-19). Understanding …
[PDF][PDF] Neutralization potency of monoclonal antibodies recognizing dominant and subdominant epitopes on SARS-CoV-2 Spike is impacted by the B. 1.1. 7 variant
C Graham, J Seow, I Huettner, H Khan, N Kouphou… - Immunity, 2021 - cell.com
Interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the receptor ACE2
on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
A potent neutralizing human antibody reveals the N-terminal domain of the Spike protein of SARS-CoV-2 as a site of vulnerability
X Chi, R Yan, J Zhang, G Zhang, Y Zhang, M Hao… - BioRxiv, 2020 - biorxiv.org
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) presents a global public health threat. Most …
syndrome coronavirus 2 (SARS-CoV-2) presents a global public health threat. Most …
Cryptic-site-specific antibodies to the SARS-CoV-2 receptor binding domain can retain functional binding affinity to spike variants
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has accumulated more than
700 million infection cases and 6.9 million deaths. New variants have affected antibody …
700 million infection cases and 6.9 million deaths. New variants have affected antibody …
A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
Vaccines and therapeutics are urgently needed for the pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …
respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we screen human monoclonal …
[HTML][HTML] Impact of the B. 1.1. 7 variant on neutralizing monoclonal antibodies recognizing diverse epitopes on SARS-CoV-2 Spike
C Graham, J Seow, I Huettner, H Khan, N Kouphou… - bioRxiv, 2021 - ncbi.nlm.nih.gov
The interaction of the SARS-CoV-2 Spike receptor binding domain (RBD) with the ACE2
receptor on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
receptor on host cells is essential for viral entry. RBD is the dominant target for neutralizing …
Uncovering a conserved vulnerability site in SARS‐CoV‐2 by a human antibody
T Li, H Cai, Y Zhao, Y Li, Y Lai, H Yao… - EMBO Molecular …, 2021 - embopress.org
An essential step for SARS‐CoV‐2 infection is the attachment to the host cell receptor by its
Spike receptor‐binding domain (RBD). Most of the existing RBD‐targeting neutralizing …
Spike receptor‐binding domain (RBD). Most of the existing RBD‐targeting neutralizing …
[PDF][PDF] Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for …
CoV-2 infection is crucial for understanding immune protection and identifying targets for …