Review of technological challenges in personalised medicine and early diagnosis of neurodegenerative disorders

C Domínguez-Fernández, J Egiguren-Ortiz… - International Journal of …, 2023 - mdpi.com
Neurodegenerative disorders are characterised by progressive neuron loss in specific brain
areas. The most common are Alzheimer's disease and Parkinson's disease; in both cases …

Imaging biomarkers in neurodegeneration: current and future practices

PNE Young, M Estarellas, E Coomans… - Alzheimer's research & …, 2020 - Springer
There is an increasing role for biological markers (biomarkers) in the understanding and
diagnosis of neurodegenerative disorders. The application of imaging biomarkers …

Positron emission tomography (PET) and neuroimaging in the personalized approach to neurodegenerative causes of dementia

M Ricci, A Cimini, A Chiaravalloti, L Filippi… - International Journal of …, 2020 - mdpi.com
Generally, dementia should be considered an acquired syndrome, with multiple possible
causes, rather than a specific disease in itself. The leading causes of dementia are …

Modern methods of diagnostics and treatment of neurodegenerative diseases and depression

N Shusharina, D Yukhnenko, S Botman, V Sapunov… - Diagnostics, 2023 - mdpi.com
This paper discusses the promising areas of research into machine learning applications for
the prevention and correction of neurodegenerative and depressive disorders. These two …

Artificial Intelligence in The Management of Neurodegenerative Disorders

S Dhankhar, S Mujwar, N Garg… - CNS & Neurological …, 2024 - ingentaconnect.com
Neurodegenerative disorders are characterized by a gradual but irreversible loss of
neurological function. The ability to detect and treat these conditions successfully is crucial …

From biomarkers to precision medicine in neurodegenerative diseases: where are we?

G Tondo, F De Marchi - Journal of Clinical Medicine, 2022 - mdpi.com
The biomarkers era grew in the last two decades when several technical and
methodological advances have improved the research in neurodegenerative diseases. All …

Molecular and imaging biomarkers in Alzheimer's disease: a focus on recent insights

C Villa, M Lavitrano, E Salvatore, R Combi - Journal of Personalized …, 2020 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly, affecting millions of people worldwide and clinically characterized by a progressive …

Detection of Alzheimer's disease onset using MRI and PET neuroimaging: longitudinal data analysis and machine learning

I Aberathne, D Kulasiri… - Neural Regeneration …, 2023 - journals.lww.com
The scientists are dedicated to studying the detection of Alzheimer's disease onset to find a
cure, or at the very least, medication that can slow the progression of the disease. This …

Personalized medicine in neurodegenerative diseases: how far away?

K Gotovac, S Hajnšek, MB Pašić, N Pivac… - Molecular diagnosis & …, 2014 - Springer
Neurodegenerative diseases are characterized by progressive dysfunction of the nervous
system as a result of neuronal loss in the brain and spinal cord. Despite extensive research …

The emerging role of proteomics in precision medicine: applications in neurodegenerative diseases and neurotrauma

R Alaaeddine, M Fayad, E Nehme, HF Bahmad… - … Medicine: Lessons from …, 2017 - Springer
Inter-individual variability in response to pharmacotherapy has provoked a higher demand
to personalize medical decisions. As the field of pharmacogenomics has served to translate …