Cancer involves cells' abnormal growth and ability to invade or metastasize to different body
parts. Cancerous cells can divide uncontrollably and spread to other areas through the …

Cancer immunotherapy offers substantive benefit to patients with various tumour types, in
some cases leading to complete tumour clearance. However, many patients do not respond …

The immune system is tasked with identifying malignant cells to eliminate or prevent cancer
spread. This involves a complex orchestration of many immune cell types that together …

Interferon-gamma (IFN-γ) is a pleiotropic molecule with associated antiproliferative, pro-
apoptotic and antitumor mechanisms. This effector cytokine, often considered as a major …

Interferon-γ (IFN-γ) is a pleiotropic cytokine that has long been praised as an important
effector molecule of anti-tumor immunity, capable of suppressing tumor growth through …

Originally identified in studies of cellular resistance to viral infection, interferon (IFN)-γ is now
known to represent a distinct member of the IFN family and plays critical roles not only in …

Interferons (IFNs) are a large family of pleiotropic cytokines that regulate both innate and
adaptive immunity and show anti-cancer effects in various cancer types. Moreover, it was …

Interferon gamma has long been studied as a critical mediator of tumor immunity. In recent
years, the complexity of cellular interactions that take place in the tumor microenvironment …

Homeostatic programs balance immune protection and self-tolerance. Such mechanisms
likely impact autoimmunity and tumor formation, respectively. How homeostasis is …

Interferon-gamma (IFNγ) is a cytokine that plays physiologically important roles in promoting
innate and adaptive immune responses. The absence of IFNγ production or cellular …