The many functional partnerships and interactions that occur between proteins are at the
core of cellular processing and their systematic characterization helps to provide context in …

A system-wide understanding of cellular function requires knowledge of all functional
interactions between the expressed proteins. The STRING database aims to collect and …

Complete knowledge of all direct and indirect interactions between proteins in a given cell
would represent an important milestone towards a comprehensive description of cellular …

Much of the complexity within cells arises from functional and regulatory interactions among
proteins. The core of these interactions is increasingly known, but novel interactions …

Abstract Information on protein–protein interactions is still mostly limited to a small number of
model organisms, and originates from a wide variety of experimental and computational …

Proteins and their functional interactions form the backbone of the cellular machinery. Their
connectivity network needs to be considered for the full understanding of biological …

Functional partnerships between proteins are at the core of complex cellular phenotypes,
and the networks formed by interacting proteins provide researchers with crucial scaffolds …

A full description of a protein's function requires knowledge of all partner proteins with which
it specifically associates. From a functional perspective,'association'can mean direct physical …

Cellular life depends on a complex web of functional associations between biomolecules.
Among these associations, protein–protein interactions are particularly important due to their …

An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …