Pathoetiological model of delirium: a comprehensive understanding of the neurobiology of delirium and an evidence-based approach to prevention and treatment

JR Maldonado - Critical care clinics, 2008 - Elsevier
Delirium is the most common complication found in the general hospital setting. Yet, we
know relatively little about its actual pathophysiology. This article contains a summary of …

[HTML][HTML] Insight into delirium

S Ali, M Patel, S Jabeen, RK Bailey, T Patel… - Innovations in clinical …, 2011 - ncbi.nlm.nih.gov
Delirium is a common and serious disorder with high morbidity and mortality. It occurs in 35
to 80 percent of critically ill, hospitalized patients. It may lead to mortality if not detected early …

Delirium in the intensive care unit: a review

A Morandi, JC Jackson - Neurologic Clinics, 2011 - neurologic.theclinics.com
This article provides an overview of the literature currently available concerning the
epidemiology, definition, diagnosis, pathophysiology, and the management of delirium, with …

Delirium in the acute care setting: characteristics, diagnosis and treatment

JR Maldonado - Critical care clinics, 2008 - Elsevier
Delirium is a neurobehavioral syndrome caused by the transient disruption of normal
neuronal activity secondary to systemic disturbances. It is also the most common psychiatric …

Etiology and management of delirium

NM Kaplan, BF Palmer, V Roche - The American journal of the medical …, 2003 - Elsevier
Delirium has been recognized for the last 3 millennia and is the most common complication
found in hospitalized patients aged 65 and older in the United States. However, critical basic …

[HTML][HTML] The intensive care delirium research agenda: a multinational, interprofessional perspective

PP Pandharipande, EW Ely, RC Arora, MC Balas… - Intensive care …, 2017 - Springer
Delirium, a prevalent organ dysfunction in critically ill patients, is independently associated
with increased morbidity. This last decade has witnessed an exponential growth in delirium …

[HTML][HTML] Pharmacological and nonpharmacological management of delirium in critically ill patients

DM Hipp, EW Ely - Neurotherapeutics, 2012 - Elsevier
Delirium is a common yet under-diagnosed syndrome of acute brain dysfunction, which is
characterized by inattention, fluctuating mental status, altered level of consciousness, or …

[HTML][HTML] Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression

EML Bowman, EL Cunningham, VJ Page, DF McAuley - Critical Care, 2021 - Springer
Delirium is a clinical syndrome occurring in heterogeneous patient populations. It affects 45–
87% of critical care patients and is often associated with adverse outcomes including …

Pathophysiology review: seven neurotransmitters associated with delirium

MA Mulkey, SR Hardin, DWM Olson… - Clinical Nurse …, 2018 - journals.lww.com
Abstract Delirium affects 70% to 80% of intensive care unit patients and is associated with a
10-fold increase in rates of cognitive impairment at discharge and a 3-fold increase in …

Managing ICU delirium

A Schiemann, D Hadzidiakos… - Current opinion in critical …, 2011 - journals.lww.com
Managing ICU delirium : Current Opinion in Critical Care Managing ICU delirium : Current
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