Efficacy and safety of human umbilical cord-derived mesenchymal stem cells for COVID-19 pneumonia: a meta-analysis of randomized controlled trials

Q Liu, F Ma, Y Zhong, G Wang, L Hu, Y Zhang… - Stem Cell Research & …, 2023 - Springer
Background Elevated levels of inflammatory factors are associated with poor prognosis in
coronavirus disease-19 (COVID-19). However, mesenchymal stem cells (MSCs) have …

[HTML][HTML] Efficacy and safety of umbilical cord mesenchymal stem cells for the treatment of patients with COVID-19

F Wei, D Kong, T Li, A Li, Y Tan, J Fang, X Zhuang… - Clinics, 2021 - SciELO Brasil
OBJECTIVES: The coronavirus disease (COVID-19) outbreak has catastrophically
threatened public health worldwide and presented great challenges for clinicians. To date …

Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: A double-blind, phase 1/2a, randomized controlled trial

G Lanzoni, E Linetsky, D Correa… - Stem cells …, 2021 - academic.oup.com
Acute respiratory distress syndrome (ARDS) in COVID-19 is associated with high mortality.
Mesenchymal stem cells are known to exert immunomodulatory and anti-inflammatory …

Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19: a phase 1 clinical trial

F Meng, R Xu, S Wang, Z Xu, C Zhang, Y Li… - Signal transduction and …, 2020 - nature.com
No effective drug treatments are available for coronavirus disease 2019 (COVID-19). Host-
directed therapies targeting the underlying aberrant immune responses leading to …

Efficacy of umbilical cord mesenchymal stromal cells for COVID-19: A systematic review and meta-analysis

C Yang, R Chen, Q Zhu, S Han, M Kuang - Frontiers in Immunology, 2022 - frontiersin.org
Objectives A major challenge for COVID-19 therapy is dysregulated immune response
associated with the disease. Umbilical cord mesenchymal stromal cells (UC-MSCs) may be …

One-year follow-up study after patients with severe COVID-19 received human umbilical cord mesenchymal stem cells treatment

L Shi, Y Zheng, Z Cheng, N Ji, C Niu, Y Wang… - Stem Cell Research & …, 2022 - Springer
Background The novel coronavirus is still mutating, and the pandemic continues.
Meanwhile, many COVID-19 survivors have residual postinfection clinical manifestations …

Treatment with Human Umbilical Cord-Derived Mesenchymal Stem Cells for Severe COVID-19 Patients with Lung Damage: A Randomised, Double-Blind, Placebo …

L Shi, H Huang, X Lu, X Yan, X Jiang, R Xu, S Wang… - 2020 - papers.ssrn.com
Background: Treatment of severe Corona Virus Disease 2019 (COVID-19) is challenging.
We performed a phase 2 trial to assess the efficacy and safety of human umbilical cord …

Umbilical cord mesenchymal stem cells for COVID-19 ARDS: a double blind, phase 1/2a, randomized controlled trial

G Lanzoni, E Linetsky, D Correa, SM Cayetano… - 2020 - papers.ssrn.com
Background: Acute Respiratory Distress Syndrome (ARDS) in COVID-19 is associated with
high mortality. Mesenchymal Stem Cells (MSC) are potent immunomodulatory cells. The aim …

[HTML][HTML] Phase 1 clinical trial for intravenous administration of mesenchymal stem cells derived from umbilical cord and placenta in patients with moderate COVID-19 …

A Sharma, R Kulkarni, H Sane, N Awad… - American journal of …, 2022 - ncbi.nlm.nih.gov
Objective: Mesenchymal stem cells can serve as a therapeutic option for COVID-19. Their
immunomodulatory and anti-inflammatory properties can regulate the exaggerated …

Human umbilical cord mesenchymal stromal cell treatment of severe COVID-19 patients: a 3-month follow-up study following hospital discharge

G Feng, L Shi, T Huang, N Ji, Y Zheng… - Stem Cells and …, 2021 - liebertpub.com
Previously, we demonstrated the therapeutic effects of human umbilical cord mesenchymal
stromal cells (hUC-MSCs) in severe coronavirus disease 2019 (COVID-19) patients. In this 3 …