The global transmission network of HIV-1

JO Wertheim, AJ Leigh Brown, NL Hepler… - The Journal of …, 2014 - academic.oup.com
Human immunodeficiency virus type 1 (HIV-1) is pandemic, but its contemporary global
transmission network has not been characterized. A better understanding of the properties …

Defining HIV-1 transmission clusters based on sequence data

AS Hassan, OG Pybus, EJ Sanders, J Albert… - Aids, 2017 - journals.lww.com
Understanding HIV-1 transmission dynamics is relevant to both screening and intervention
strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based …

HIV-TRACE (TRAnsmission Cluster Engine): a tool for large scale molecular epidemiology of HIV-1 and other rapidly evolving pathogens

SL Kosakovsky Pond, S Weaver… - Molecular biology …, 2018 - academic.oup.com
In modern applications of molecular epidemiology, genetic sequence data are routinely
used to identify clusters of transmission in rapidly evolving pathogens, most notably HIV-1 …

A novel methodology for large-scale phylogeny partition

MCF Prosperi, M Ciccozzi, I Fanti, F Saladini… - Nature …, 2011 - nature.com
Understanding the determinants of virus transmission is a fundamental step for effective
design of screening and intervention strategies to control viral epidemics. Phylogenetic …

Molecular network-based intervention brings us closer to ending the HIV pandemic

X Han, B Zhao, M An, P Zhong, H Shang - Frontiers of Medicine, 2020 - Springer
Precise identification of HIV transmission among populations is a key step in public health
responses. However, the HIV transmission network is usually difficult to determine. HIV …

Phylogenetic studies of transmission dynamics in generalized HIV epidemics: an essential tool where the burden is greatest?

AM Dennis, JT Herbeck, AL Brown… - JAIDS Journal of …, 2014 - journals.lww.com
Efficient and effective HIV prevention measures for generalized epidemics in sub-Saharan
Africa have not yet been validated at the population level. Design and impact evaluation of …

Identifying clusters of recent and rapid HIV transmission through analysis of molecular surveillance data

AM Oster, AM France, N Panneer… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Detecting recent and rapid spread of HIV can help prioritize prevention and
early treatment for those at highest risk of transmission. HIV genetic sequence data can …

Growth of HIV-1 molecular transmission clusters in New York City

JO Wertheim, B Murrell, SR Mehta… - The Journal of …, 2018 - academic.oup.com
Background HIV-1 genetic sequences can be used to infer viral transmission history and
dynamics. Throughout the United States, HIV-1 sequences from drug resistance testing are …

Phylogenetic tools for generalized HIV-1 epidemics: findings from the PANGEA-HIV methods comparison

O Ratmann, EB Hodcroft, M Pickles… - Molecular biology …, 2017 - academic.oup.com
Viral phylogenetic methods contribute to understanding how HIV spreads in populations,
and thereby help guide the design of prevention interventions. So far, most analyses have …

Comparative circulation dynamics of the five main HIV types in China

B Vrancken, B Zhao, X Li, X Han, H Liu, J Zhao… - Journal of …, 2020 - Am Soc Microbiol
The HIV epidemic in China accounts for 3% of the global HIV incidence. We compared the
patterns and determinants of interprovincial spread of the five most prevalent circulating …