Infectious diseases continue to inflict a high global disease burden. The consensus is that
vaccination is the most effective option against infectious diseases. Oral vaccines have …

While vaccination remains the most cost effective strategy for disease prevention,
communicable diseases persist as the second leading cause of death worldwide. There is a …

Although most commercial vaccines are delivered by injection, there is an increasing
interest in needle-free vaccine delivery for reasons including the ability to elicit immune …

The oral route is the ideal means of delivering prophylactic and therapeutic vaccines,
offering significant advantages over systemic delivery. Most notably, oral delivery is …

Oral vaccination enables pain-free and self-administrable vaccine delivery for rapid mass
vaccination during pandemic outbreaks. Furthermore, it elicits systemic and mucosal …

Most currently available commercial vaccines are delivered by systemic injection. However,
needle-free oral vaccine delivery is currently of great interest for several reasons, including …

Vaccines have been one of the most far-reaching and important public health initiatives of
the 20th century. Yet as we move into the 21st century, millions of people still die from …

As early as 900 years ago, the Bedouins of the Negev desert were reported to kill a rabid
dog, roast its liver and feed it to a dog-bitten person for three to five days according to the …

While the majority of human pathogens infect the body through mucosal sites, most licensed
vaccines are injectable. In fact the only mucosal vaccine that has been widely used globally …

In developing countries, oral immunization is more readily accepted than parenteral, as it
accompanies the ease and safety of administration and induces the desired mucosal …