It has been five years since the elucidation of the genetic mutation underlying the
pathogenesis of Huntington's disease (HD)(97), however the precise mechanism of the …

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder with midlife
onset characterized by psychiatric, cognitive, and motor symptoms. Death occurs between …

We review recent advances regarding the pathogenesis of Huntington's disease (HD). This
genetic neurodegenerative disorder is caused by an expanded CAG repeat in a gene …

Huntington's disease (HD) is an autosomal dominant inherited neurodegenerative disorder
with relentless course and prototypical clinical symptoms. In 1993 HD was associated with …

To gain insight into the pathogenic mechanisms of Huntington's disease (HD), we have
developed a stable cellular model, using a neuroblastoma cell line in which the expression …

Huntington's disease (HD) is a neurodegenerative hereditary illness originated by the
mutation of the gene encoding the huntingtin-protein (htt). Mutated htt (mhtt) is characterized …

Huntington's disease (HD) is a devastating autosomal dominant neurodegenerative disease
caused by a CAG trinucleotide repeat expansion encoding an abnormally long …

The etiology of the selective neuronal death that occurs in Huntington's disease (HD) is
unknown. Several lines of evidence implicate the involvement of energetic defects and …

Huntington's disease (HD) is a devastating neurodegenerative disorder characterized by the
progressive development of involuntary choreiform movements, cognitive impairment …

Huntington's disease (HD) is an inherited genetic disorder, characterized by cognitive
dysfunction and abnormal body movements called chorea. George Huntington, an Ohio …