Adenoviral-vectored next-generation respiratory mucosal vaccines against COVID-19
The world is in need of next-generation COVID-19 vaccines. Although first-generation
injectable COVID-19 vaccines continue to be critical tools in controlling the current global …
injectable COVID-19 vaccines continue to be critical tools in controlling the current global …
[PDF][PDF] Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
Viral-vectored respiratory mucosal vaccine strategies
Increasing global concerns of pandemic respiratory viruses highlight the importance of
developing optimal vaccination strategies that encompass vaccine platform, delivery route …
developing optimal vaccination strategies that encompass vaccine platform, delivery route …
[HTML][HTML] Intranasal delivery of an adenovirus-vector vaccine co-expressing a modified spike protein and a genetic adjuvant confers lasting mucosal immunity against …
The ongoing COVID-19 pandemic caused by SARS-CoV-2 infection has threatened global
health. Since the first case of infection was reported in December 2019, SARS-CoV-2 has …
health. Since the first case of infection was reported in December 2019, SARS-CoV-2 has …
[HTML][HTML] Adenoviral vector vaccine platforms in the SARS-CoV-2 pandemic
Adenoviral vectors have been explored as vaccine agents for a range of infectious diseases,
and their ability to induce a potent and balanced immune response made them logical …
and their ability to induce a potent and balanced immune response made them logical …
[HTML][HTML] Mucosal COVID-19 vaccines: Risks, benefits and control of the pandemic
D Miteva, M Peshevska-Sekulovska… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Based on mucosal immunization to promote both mucosal and systemic immune responses,
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …
[HTML][HTML] Promises and challenges of mucosal COVID-19 vaccines
APS Rathore, ALS John - vaccine, 2023 - Elsevier
Abstract Coronavirus disease-2019 (COVID-19) is an ongoing pandemic caused by the
newly emerged virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
newly emerged virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
[HTML][HTML] Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines
V Mouro, A Fischer - Mucosal immunology, 2022 - Elsevier
The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
A bacteriophage-based, highly efficacious, needle-and adjuvant-free, mucosal COVID-19 vaccine
ABSTRACT The US Food and Drug Administration-authorized mRNA-and adenovirus-
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …
based SARS-CoV-2 vaccines are intramuscularly injected in two doses and effective in …
[HTML][HTML] Next generation mucosal vaccine strategy for respiratory pathogens
F Dotiwala, AK Upadhyay - Vaccines, 2023 - mdpi.com
Inducing humoral and cytotoxic mucosal immunity at the sites of pathogen entry has the
potential to prevent the infection from getting established. This is different from systemic …
potential to prevent the infection from getting established. This is different from systemic …