COVID‐19 metabolism: Mechanisms and therapeutic targets

T Wang, Y Cao, H Zhang, Z Wang, CH Man… - MedComm, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) dysregulates antiviral
signaling, immune response, and cell metabolism in human body. Viral genome and …

[HTML][HTML] Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

P Chen, M Wu, Y He, B Jiang, ML He - Signal Transduction and …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

[HTML][HTML] Can a metabolism-targeted therapeutic intervention successfully subjugate SARS-COV-2? A scientific rational

K Mansouri, M Rastegari-Pouyani… - Biomedicine & …, 2020 - Elsevier
As a process entailing a high turnover of the host cell molecules, viral replication is required
for a successful viral infection and requests virus capacity to acquire the macromolecules …

[HTML][HTML] Metabolic perturbation associated with COVID-19 disease severity and SARS-CoV-2 replication

S Krishnan, H Nordqvist, AT Ambikan, S Gupta… - Molecular & Cellular …, 2021 - ASBMB
Viruses hijack host metabolic pathways for their replicative advantage. In this study, using
patient-derived multiomics data and in vitro infection assays, we aimed to understand the …

[HTML][HTML] A metabolic handbook for the COVID-19 pandemic

JS Ayres - Nature metabolism, 2020 - nature.com
For infectious-disease outbreaks, clinical solutions typically focus on efficient pathogen
destruction. However, the COVID-19 pandemic provides a reminder that infectious diseases …

[HTML][HTML] Susceptibility to Metabolic Diseases in COVID-19: To be or Not to be an Issue

M Kaviani, S Keshtkar, S Soleimanian… - Frontiers in Molecular …, 2022 - frontiersin.org
Despite the passage of more than 17 months from the beginning of the COVID-19 pandemic,
challenges regarding the disease and its related complications still continue in recovered …

A data-driven hypothesis on the epigenetic dysregulation of host metabolism by SARS coronaviral infection: potential implications for the SARS-CoV-2 modus …

GD Vavougios - Medical Hypotheses, 2020 - Elsevier
COVID-19, the disease caused by the novel SARS-CoV-2, a betacoronavirus structurally
similar to SARS-CoV. Based on both structural and syndromic similarities with SARS-CoV, a …

Host metabolic reprogramming in response to SARS-CoV-2 infection: A systems biology approach

STR Moolamalla, R Balasubramanian, R Chauhan… - Microbial …, 2021 - Elsevier
Understanding the pathogenesis of SARS-CoV-2 is essential for developing effective
treatment strategies. Viruses hijack the host metabolism to redirect the resources for their …

[HTML][HTML] Metabolic reprogramming in COVID-19

T Shen, T Wang - International journal of molecular sciences, 2021 - mdpi.com
Plenty of research has revealed virus induced alternations in metabolic pathways, which is
known as metabolic reprogramming. Studies focusing on COVID-19 have uncovered …

Coronavirus disease 2019 (COVID‐19) update: From metabolic reprogramming to immunometabolism

M Rudiansyah, SA Jasim… - Journal of Medical …, 2022 - Wiley Online Library
The field of immunometabolism investigates and describes the effects of metabolic rewiring
in immune cells throughout activation and the fates of these cells. Recently, it has been …