Upregulation of type 1 conventional dendritic cells implicates antigen cross-presentation in multisystem inflammatory syndrome

JJ Huang, SB Gaines, ML Amezcua, TR Lubell… - Journal of Allergy and …, 2022 - Elsevier
Background Multisystem inflammatory syndrome in children (MIS-C) is an acute, febrile,
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated syndrome …

[PDF][PDF] Mapping systemic inflammation and antibody responses in multisystem inflammatory syndrome in children (MIS-C)

CN Gruber, RS Patel, R Trachtman, L Lepow, F Amanat… - Cell, 2020 - cell.com
Initially, children were thought to be spared from disease caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). However, a month into the epidemic, a novel …

The potential threat of multisystem inflammatory syndrome in children during the COVID‐19 pandemic

HA Rothan, SN Byrareddy - Pediatric Allergy and Immunology, 2021 - Wiley Online Library
Multisystem inflammatory syndrome in children (MIS‐C) during the COVID‐19 pandemic
raised a global alert from the Centers for Disease Control and Prevention's Health Alert …

T cells in multisystem inflammatory syndrome in children (MIS-C) have a predominant CD4+ T helper response to SARS-CoV-2 peptides and numerous virus-specific …

LE Hsieh, J Song, A Grifoni, C Shimizu… - International Journal of …, 2022 - mdpi.com
We studied SARS-CoV-2-specific T cell responses in 22 subacute MIS-C children enrolled
in 2021 and 2022 using peptide pools derived from SARS-CoV-2 spike or nonspike …

Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS–CoV-2

C Diorio, SE Henrickson, LA Vella… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Initial reports from the severe acute respiratory coronavirus 2 (SARS–CoV-
2) pandemic described children as being less susceptible to coronavirus disease 2019 …

Enhanced Severe Acute Respiratory Syndrome Coronavirus 2 Antigen–Specific Systemic Immune Responses in Multisystem Inflammatory Syndrome in Children and …

NP Kumar, A Venkataraman, A Nancy… - The Journal of …, 2022 - academic.oup.com
Background Multisystem inflammatory syndrome in children (MIS-C) presents with
inflammation and pathology of multiple organs in the pediatric population in the weeks …

SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children

KP Lam, M Chiñas, AM Julé, M Taylor, M Ohashi… - Clinical …, 2022 - Elsevier
Multisystem inflammatory syndrome in children (MIS-C) is a severe complication of SARS-
CoV-2 infections that occurs in the pediatric population. We sought to characterize T cell …

[PDF][PDF] Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children

A Ramaswamy, NN Brodsky, TS Sumida, M Comi… - Immunity, 2021 - cell.com
Multisystem inflammatory syndrome in children (MIS-C) is a life-threatening post-infectious
complication occurring unpredictably weeks after mild or asymptomatic SARS-CoV-2 …

Distinctive phenotype of multisystem inflammatory syndrome in children associated with SARS-CoV-2 according to patients' age: a monocentric experience

A Giannattasio, F Orlando, C D'Anna, S Muzzica… - Children, 2022 - mdpi.com
Background: Multisystem inflammatory syndrome in children (MIS-C) is a disease temporally
related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and it is …

Multisystem inflammatory syndrome in US children and adolescents

LR Feldstein, EB Rose, SM Horwitz… - … England Journal of …, 2020 - Mass Medical Soc
Background Understanding the epidemiology and clinical course of multisystem
inflammatory syndrome in children (MIS-C) and its temporal association with coronavirus …