Aging is a natural phenomenon characterized by accumulation of cellular damage and debris. Oxidative stress, cellular senescence, sustained inflammation, and DNA damage are …
Cognitive decline associated with ageing and age-related disorders emerges as one of the greatest health challenges in the next decades. To date, the molecular mechanisms …
Despite remarkable scientific advancements in recent years, much about the human brain still remains a mystery, particularly in the context of brain aging and associated disorders …
Neurodegenerative diseases are incurable debilitating disorders characterized by structural and functional neuronal loss. Approximately 30 million people are affected worldwide, and …
J Lee, HJ Kim - Frontiers in aging neuroscience, 2022 - frontiersin.org
Aging is accompanied by many changes in brain and contributes to progressive cognitive decline. In contrast to pathological changes in brain, normal aging brain changes have …
K Smimih, C Azzouhri, FEZ Saad… - … and Function of Glial …, 2024 - igi-global.com
Brain aging is a complicated and diversified process that includes an ongoing decline in cognitive performance as well as various cellular and molecular changes in the brain …
Brain aging is characterized by changes at all levels, from molecules to morphology, reflected by reduced brain size, altered vasculature, and declines in motor and cognitive …
A Toledano-Díaz, MI Álvarez, A Toledano - OBM Geriatrics, 2020 - lidsen.com
Neurons, from the time of their birth until their death, are always accompanied by neuroglial cells, maintaining very close morphological and functional relationships among themselves …
MA Cherdak - Advances in Gerontology, 2023 - Springer
Brain aging is part of the aging of the whole body, largely determining the success of general aging and the quality of life of an older person. Brain aging is a complex …