Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A
multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with …

RNA is not always a faithful copy of DNA. Advances in tools enabling the interrogation of the
exact RNA sequence have permitted revision of how genetic information is transferred. We …

RNA modifications are enzymatic RNA base modifications that increase the RNA alphabet
from the 4 canonical nucleotides to more than 140 (a brief overview of RNA modifications is …

Cardiovascular disease (CVD) remains the leading cause of death in the Western world.
Despite advances in the prevention and in the management of CVD, the role of RNA …

Abstract N6-methyladenosine (m6A) is the most abundant and well-studied internal
modification of messenger RNAs among the various RNA modifications in eukaryotic cells …

N6-methyladenosine (m6A) modification is the most universal and abundant post-
transcriptional modification of eukaryotic RNA and occurs mainly at the consensus motif RR …

More than one hundred RNA modifications decorate the chemical and topological properties
of these ribose nucleotides, thereby executing their biological functions through post …

Epitranscriptomic modifications in RNA can dramatically alter the way our genetic code is
deciphered. Cells utilize these modifications not only to maintain physiological processes …

RNA transcripts are not finished products. Like proteins undergo posttranslational
modifications, RNAs undergo posttranscriptional modifications. Some of these modifications …

Abstract N6-methyladenosine (m 6 A) is the most abundant and prevalent epigenetic
modification of mRNA in mammals. This dynamic modification is regulated by m 6 A …