Pigs have substantial potential as biomedical models for studying human developmental
processes, congenital diseases, and pathogen response mechanisms in addition to utility as …

The third conference focusing on Swine in Biomedical Research was held at the Fairmont
Hotel in Chicago from January 27 to 29, 2005, to identify areas of study or methodologies …

Animal models of human diseases play a critical role in medical research. Pigs are
anatomically and physiologically more like humans than are small rodents such as mice …

Since domestication, pigs have been used extensively in agriculture and kept as companion
animals. More recently they have been used in biomedical research, given they share many …

The first transgenic pigs were generated for agricultural purposes about three decades ago.
Since then, the micromanipulation techniques of pig oocytes and embryos expanded from …

To improve the welfare of experimental animals, investigators seek to respect the 3R
principle (Replacement, Reduction, and Refinement). Even when large animal studies are …

There is a critical shortage in the number of deceased human organs that become available
for the purposes of clinical transplantation. This problem might be resolved by the …

Progress in genetic engineering over the past few decades has made it possible to develop
methods that have led to the production of transgenic animals. The development of …

Contents Experimental animals in biomedical research provide insights into disease
mechanisms and models for determining the efficacy and safety of new therapies and for …

Our current knowledge of human biology is often based on studying a wide range of animal
species. In particular, for understanding human diseases, the development of adequate …