[HTML][HTML] Monoclonal antibodies for malaria

T Wells, C Donini - New England Journal of Medicine, 2022 - Mass Medical Soc
A New Approach to Preventing Malaria Monoclonal antibodies are commonly used in the
treatment of diseases, including cancer. A next-generation antibody for the prevention of …

Monoclonal antibody: future of malaria control and prevention

S Nema, N Nitika - Transactions of The Royal Society of Tropical …, 2023 - academic.oup.com
Monoclonal antibodies (mAbs) are extremely specialized proteins that are cloned from B
cells and bind to pathogen epitopes. There are currently no known prophylactic immune …

Monoclonal antibodies for malaria prevention

M Aleshnick, M Florez-Cuadros, T Martinson… - Molecular Therapy, 2022 - cell.com
Monoclonal antibodies are highly specific proteins that are cloned from a single B cell and
bind to a single epitope on a pathogen. These laboratory-made molecules can serve as …

Antibody-based therapies for malaria

RJ Pleass, AA Holder - Nature Reviews Microbiology, 2005 - nature.com
Antibodies are multifunctional glycoproteins that are found in blood and tissue fluids, and
can protect against malaria by binding and neutralizing malaria parasites and preparing …

Integrating vaccines and monoclonal antibodies into malaria prevention

TE Taylor, F Osier - Nature Medicine, 2024 - nature.com
Integrating vaccines and monoclonal antibodies into malaria prevention | Nature Medicine
Skip to main content Thank you for visiting nature.com. You are using a browser version …

A new site of attack for a malaria vaccine

SJ Draper, MK Higgins - Nature Medicine, 2018 - nature.com
A new site of attack for a malaria vaccine | Nature Medicine Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

A monoclonal antibody for malaria prevention

MR Gaudinski, NM Berkowitz, AH Idris… - … England Journal of …, 2021 - Mass Medical Soc
Background Additional interventions are needed to reduce the morbidity and mortality
caused by malaria. Methods We conducted a two-part, phase 1 clinical trial to assess the …

Naturally Acquired Antibodies against Plasmodium falciparum: Friend or Foe?

MK Tijani, A Lugaajju, KEM Persson - Pathogens, 2021 - mdpi.com
Antibodies are central to acquired immunity against malaria. Plasmodium falciparum elicits
antibody responses against many of its protein components, but there is also formation of …

Subcutaneous administration of a monoclonal antibody to prevent malaria

K Kayentao, A Ongoiba, AC Preston… - … England Journal of …, 2024 - Mass Medical Soc
Background Subcutaneous administration of the monoclonal antibody L9LS protected adults
against controlled Plasmodium falciparum infection in a phase 1 trial. Whether a monoclonal …

Antibodies against Plasmodium falciparum malaria at the molecular level

JP Julien, H Wardemann - Nature Reviews Immunology, 2019 - nature.com
Malaria is a vector-borne disease of global importance, with the vast majority of its life-
threatening cases caused by infection with Plasmodium falciparum parasites. Repeated …