Role of triggering receptor expressed on myeloid cells-1 (TREM-1) in COVID-19 and other viral pneumonias: a systematic review and meta-analysis of clinical studies

YLM de Oliveira, A de Sá Resende… - …, 2022 - Springer
Background Triggering receptor expressed on myeloid cells-1 (TREM-1) has emerged as an
important inflammatory marker of immune response associated with severity and mortality …

sTREM-1 predicts disease severity and mortality in COVID-19 patients: involvement of peripheral blood leukocytes and MMP-8 activity

PV da Silva-Neto, JCS de Carvalho, VE Pimentel… - Viruses, 2021 - mdpi.com
Uncontrolled inflammatory responses play a critical role in coronavirus disease (COVID-19).
In this context, because the triggering-receptor expressed on myeloid cells-1 (TREM-1) is …

Potential role of triggering receptor expressed on myeloid cells-1 (TREM-1) in SARS-CoV-2 infection: first insights

A de Sá Resende, YLM de Oliveira, TR de Moura… - EXCLI journal, 2021 - excli.de
Despite of the ongoing vaccination against Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) infection, the high transmissibility and severity of coronavirus …

Soluble TREM-1 plasma concentration predicts poor outcome in COVID-19 patients

S Gibot, T Lafon, L Jacquin, B Lefevre… - Intensive Care Medicine …, 2023 - Springer
Abstract Background The immuno-receptor Triggering Expressed on Myeloid cells-1 (TREM-
1) is activated during bacterial infectious diseases, where it amplifies the inflammatory …

Evaluation of the relationship between TREM‐1/TREM‐2 ratio and clinical course in COVID‐19 pneumonia

F Kerget, B Kerget, S İba Yılmaz… - International journal of …, 2021 - Wiley Online Library
Objective The inflammatory/anti‐inflammatory balance has an important role in the clinical
course of SARS‐CoV‐2 infection (COVID‐19), which has affected over 100 million people …

Prognostic value of sTREM-1 in COVID-19 patients: a biomarker for disease severity and mortality

PV da Silva Neto, JCS de Carvalho, VE Pimentel… - medRxiv, 2020 - medrxiv.org
Background The uncontrolled inflammatory response plays a critical role in the novel
coronavirus disease (COVID-19) and triggering receptor expressed on myeloid cells-1 …

TREM-1, TREM-2 and their association with disease severity in patients with COVID-19

R Fan, Z Cheng, Z Huang, Y Yang, N Sun, B Hu… - Annals of …, 2023 - Taylor & Francis
Background Delayed diagnosis and inadequate treatment caused by limited biomarkers are
associated with the outcomes of COVID-19 patients. It is necessary to identify other …

Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19

AH de Nooijer, I Grondman, S Lambden… - Bioscience …, 2021 - portlandpress.com
Patients with sepsis display increased concentrations of sTREM-1 (soluble Triggering
Receptor Expressed on Myeloid cells 1), and a phase II clinical trial focusing on TREM-1 …

TREM-2 is a sensor and activator of T cell response in SARS-CoV-2 infection

Y Wu, M Wang, H Yin, S Ming, X Li, G Jiang, Y Liu… - Science …, 2021 - science.org
Limited understanding of T cell responses against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has impeded vaccine development and drug discovery for …

sTREM-1 as a Predictive Biomarker for Disease Severity and Prognosis in COVID-19 Patients

N Geng, Z Wu, Z Liu, W Pan, Y Zhu, H Shi… - Journal of …, 2024 - Taylor & Francis
Background Research on biomarkers associated with the severity and adverse prognosis of
COVID-19 can be beneficial for improving patient outcomes. However, there is limited …