The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

The liver plays a key role in maintaining energy homeostasis by sensing and responding to
changes in nutrient status under various metabolic conditions. Recently highlighted as a …

Hepatic steatosis is an underlying feature of nonalcoholic fatty liver disease (NAFLD), which
is the most common form of liver disease and is present in up to∼ 70% of individuals who …

Insulin resistance is one of the key components of the metabolic syndrome and it eventually
leads to the development of type 2 diabetes, making it one of the biggest medical problems …

Nonalcoholic fatty liver disease (NAFLD) refers to a spectrum of liver damage ranging from
simple steatosis to nonalcoholic steatohepatitis (NASH), advanced fibrosis and cirrhosis …

Industrialized society-caused dysregular human behaviors and activities such as
overworking, excessive dietary intake, and sleep deprivation lead to perturbations in the …

Over the last decade, the understanding of the association between insulin resistance (IR)
and non-alcoholic fatty liver disease (NAFLD) has dramatically evolved. There is clear …

Insulin resistance (IR) is the pathophysiological hallmark of nonalcoholic fatty liver disease
(NAFLD), one of the most common causes of chronic liver disease in Western countries. We …

Obesity is less common in the Asian population, but Asian people may be susceptible to
obesity-associated metabolic dysregulation. Accumulating evidence suggests that insulin …

Non-alcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease in
Western countries, ranging from simple steatosis to steatohepatitis, cirrhosis, and …