Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …

DNA methylation is implicated in modulating gene transcription in a wide array of taxa.
However, a complete understanding of the specific function of DNA methylation requires …

The field of molecular biology is advancing fast with new powerful technologies, sequencing
methods and analysis software being developed constantly. Commonly used tools originally …

Background Cytosine DNA methylation is a heritable epigenetic mark present in most
eukaryotic groups. While the patterns and functions of DNA methylation have been …

Epigenetic mechanisms traditionally have been studied in the domains of development and
disease, but they may also play important roles in ecological and evolutionary processes. In …

DNA methylation is a key epigenetic modification in the vertebrate genomes known to be
involved in biological processes such as regulation of gene expression, DNA structure and …

Patterns of DNA methylation in animal genomes are known to vary from an apparent
absence of modified bases, via methylation of a minor fraction of the genome, to genome …

DNA methylation refers to the addition of a methyl group to nucleotides within DNA. As with
other epigenetic endpoints, patterns of DNA methylation are susceptible to alterations due to …

Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA
methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is …

Cytosine methylation is an ancient epigenetic modification yet its function and extent within
genomes is highly variable across eukaryotes. In mammals, methylation controls …