Escitalopram in adolescents with generalized anxiety disorder: a double-blind, randomized, placebo-controlled study

JR Strawn, JA Mills, H Schroeder… - The Journal of clinical …, 2020 - psychiatrist.com
Background: Selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat
pediatric anxiety disorders, including generalized anxiety disorder (GAD); however, their …

A multicenter double-blind, placebo-controlled trial of escitalopram in children and adolescents with generalized anxiety disorder

JR Strawn, L Moldauer, RD Hahn, A Wise… - Journal of Child and …, 2023 - liebertpub.com
Objective: Generalized anxiety disorder (GAD) in children and adolescents is associated
with substantial morbidity and increases the risk of future psychopathology. However …

Influence of CYP2C19 metabolizer status on escitalopram/citalopram tolerability and response in youth with anxiety and depressive disorders

SL Aldrich, EA Poweleit, CA Prows, LJ Martin… - Frontiers in …, 2019 - frontiersin.org
In pediatric patients, the selective serotonin reuptake inhibitors (SSRIs) escitalopram and
citalopram (es/citalopram) are commonly prescribed for anxiety and depressive disorders …

Acute neurofunctional effects of escitalopram in pediatric anxiety: a double-blind, placebo-controlled trial

L Lu, JA Mills, H Li, HK Schroeder, SA Mossman… - Journal of the American …, 2021 - Elsevier
Objective Amygdala− ventrolateral prefrontal cortex (VLPFC) circuitry is disrupted in
pediatric anxiety disorders, yet how selective serotonin reuptake inhibitors (SSRIs) affect this …

Escitalopram in the treatment of adolescent depression: a randomized placebo-controlled multisite trial

GJ Emslie, D Ventura, A Korotzer… - Journal of the American …, 2009 - Elsevier
OBJECTIVE: This article presents the results from a prospective, randomized, double-blind,
placebo-controlled trial of escitalopram in adolescent patients with major depressive …

Escitalopram in the treatment of adolescent depression: a randomized, double-blind, placebo-controlled extension trial

RL Findling, A Robb, A Bose - Journal of child and adolescent …, 2013 - liebertpub.com
Objective: The purpose of this study was to evaluate the extended efficacy, safety, and
tolerability of escitalopram relative to placebo in adolescents with major depressive disorder …

A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression

KD Wagner, J Jonas, RL Findling, D Ventura… - Journal of the American …, 2006 - Elsevier
OBJECTIVE: Escitalopram is a selective serotonin reuptake inhibitor antidepressant
indicated for use in adults. This trial examined the efficacy and safety of escitalopram in …

CYP2C19-guided escitalopram and sertraline dosing in pediatric patients: a pharmacokinetic modeling study

JR Strawn, EA Poweleit, LB Ramsey - Journal of child and …, 2019 - liebertpub.com
Abstract Objective: Cytochrome P4502C19 (CYP2C19) is a highly polymorphic gene that
encodes an enzyme that metabolizes escitalopram and sertraline, two selective serotonin …

Escitalopram in the treatment of generalized anxiety disorder: Double‐blind, placebo controlled, flexible‐dose study

JRT Davidson, A Bose, A Korotzer… - Depression and …, 2004 - Wiley Online Library
Escitalopram has been shown in clinical trials to improve anxiety symptoms associated with
depression, panic disorder, and social anxiety disorder. This study was designed to evaluate …

Treatment of generalized anxiety disorder with escitalopram: pooled results from double-blind, placebo-controlled trials

WK Goodman, A Bose, Q Wang - Journal of Affective Disorders, 2005 - Elsevier
BACKGROUND: Escitalopram 10 mg/day is an effective and well-tolerated antidepressant.
Three randomized controlled trials recently evaluated the safety and efficacy of escitalopram …