Whereas the diagnosis of moderate and severe traumatic brain injury (TBI) is readily visible
on current medical imaging paradigms (magnetic resonance imaging [MRI] and computed …

We have previously reported long-term changes in the brains of non-concussed varsity
rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) …

Mild traumatic brain injury (mTBI) or sport‐induced concussion has recently become a
prominent concern not only in the athletic setting (ie sports venue) but also in the general …

The blood–brain barrier (BBB) is an anatomical microstructural unit, with several different
components playing key roles in normal brain physiological regulation. Formed by tightly …

✓ The authors posit that cellular edema is the major contributor to brain swelling in diffuse
head injury and that the contribution of vasogenic edema may be overemphasized. The …

There is still controversy in the literature whether a single episode of mild traumatic brain
injury (mTBI) results in short-and/or long-term functional and structural deficits in the …

The midbrain is biomechanically susceptible to force loading from repetitive subconcussive
head impacts (RSHI), is a site of tauopathy in chronic traumatic encephalopathy (CTE), and …

Traumatic brain injury (TBI) is the leading cause of death in young adults and children. The
treatment of TBI in the acute phase has improved substantially; however, the prevention and …

Although concussion is now recognized as a major health issue, its non-lethal nature has
limited characterization of the underlying pathophysiology. In particular, potential …

Mild blast-induced traumatic brain injury (TBI) is associated with blood-brain barrier (BBB)
disruption. However, the mechanisms whereby blast disrupts BBB integrity are not well …