Although vitamin D has been implicated in cardiovascular protection, few studies have
addressed the role of vitamin D receptor (VDR) in atherosclerosis. Here we investigate the …

Multiple epidemiological studies link vitamin D deficiency to increased cardiovascular
disease (CVD), but causality and possible mechanisms underlying these associations are …

Vitamin D deficiency has been associated with cardiovascular dysfunction. We evaluated
the role of the vitamin D receptor (VDR) in vascular endothelial function, a marker of …

Intense effort has been devoted to understanding predisposition to chronic systemic
inflammation because it contributes to cardiometabolic disease. We demonstrate that …

Endothelial cell activation leading to leukocyte recruitment and adhesion plays an essential
role in the initiation and progression of atherosclerosis. Vitamin D has cardioprotective …

Vitamin D plays an essential role in calcium homeostasis and bone metabolism, but recent
research has exposed a larger spectrum of biological actions that also includes induction of …

Vitamin D, as a natural medicine, is known to regulate calcium and phosphate homeostasis.
But abundant research has shown that vitamin D also plays a regulatory role in …

Vitamin D insufficiency has been reported to be associated with increased blood cholesterol
concentrations. Here we used two strains of VDR knock-out (VDR-KO) mice to study whether …

Background—A growing body of evidence from animal studies supports the hypothesis that
oxidative stress-mediated mechanisms play a central role in early atherogenesis. In contrast …

OBJECTIVE: The activated vitamin D receptor (VDR) may have an important role in vascular
health. The objective of this study was to determine whether there is an association between …