Chronic inflammation, which is called “inflamm-aging”, is characterized by an increased
level of inflammatory cytokines in response to physiological and environmental stressors …

Aging is a complex process that results from a combination of environmental, genetic, and
epigenetic factors. A chronic pro-inflammatory status is a pervasive feature of aging. This …

Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Aging and inflammation both contribute pivotally to cardiovascular (CV) and cerebrovascular
disease, the leading causes of death and disability worldwide. The concept of inflamm-aging …

The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

The last 10 y have seen an enormous surge in research focused on inflammation and
atherosclerotic heart disease. In parallel, inflammation (used as a term to represent a broad …

Frailty is a progressive physiologic decline in multiple body systems marked by loss of
function, loss of physiologic reserve, and increased vulnerability to disease and death. Until …

The pathogenesis of frailty and the role of inflammation is poorly understood. We examined
the evidence considering the relationship between inflammation and frailty through a …

Biological aging is characterized by a chronic low-grade inflammation level. This chronic
phenomenon has been named “inflamm-aging” and is a highly significant risk factor for …

Frailty is a term used as a marker of vulnerability, identifying individuals with a diminished
capacity to respond to external stressors. Those who are frail are at increased risk of death …