Small ubiquitin-like modifiers (SUMOs) regulate a variety of cellular processes through two
distinct mechanisms, including covalent sumoylation and non-covalent SUMO interaction …

Motivation: Post-translational modification by the Small Ubiquitin-like Modifier (SUMO)
proteins, a process termed SUMOylation, is involved in many fundamental cellular …

Systematic dissection of the sumoylation proteome is emerging as an appealing but
challenging research topic because of the significant roles sumoylation plays in cellular …

Reversible protein modification by small ubiquitin-like modifiers (SUMOs) is critical for
eukaryotic life. Mass spectrometry-based proteomics has proven effective at identifying …

Small ubiquitin-like modifiers (SUMOs) are essential for the regulation of several cellular
processes and are potential therapeutic targets owing to their involvement in diseases such …

Sumoylation has recently been identified as an important mechanism that regulates protein
interactions and localization in essential cellular functions, such as gene transcription …

Background Protein sumoylation is an essential dynamic, reversible post translational
modification that plays a role in dozens of cellular activities, especially the regulation of gene …

Small ubiquitin-like modifier (SUMO) is covalently conjugated to its target proteins thereby
altering their activity. The mammalian SUMO protein family includes four members (SUMO-1 …

SUMO ylation is a post‐translational modification that regulates a multitude of cellular
processes, including replication, cell‐cycle progression, protein transport and the DNA …

SUMO proteins are ubiquitin-related modifiers implicated in the regulation of gene
transcription, cell cycle, DNA repair, and protein localization. The molecular mechanisms by …