Multipurpose advanced split T7 promoter-based transcription amplification for ultrasensitive molecular diagnostics

J Shin, T Yoon, D Nam, D Kim, S Kim, BS Cha… - Chemical Engineering …, 2023 - Elsevier
An accurate, convenient, and rapid diagnostic platform, which can be applied in facility-
limited or point-of-care (POC) settings, is essential to help prevent the spread of infectious …

Split T7 promoter-based isothermal transcription amplification for one-step fluorescence detection of SARS-CoV-2 and emerging variants

T Yoon, J Shin, HJ Choi, KS Park - Biosensors and Bioelectronics, 2022 - Elsevier
The negative global impact of the coronavirus disease pandemic has highlighted the crucial
need for a rapid and convenient method of viral RNA detection. In this study, we report a …

An integrated microfluidic platform featuring real-time reverse transcription loop-mediated isothermal amplification for detection of COVID-19

YR Jhou, CH Wang, HP Tsai, YS Shan… - Sensors and Actuators B …, 2022 - Elsevier
An integrated microfluidic platform (IMP) utilizing real-time reverse-transcription loop-
mediated isothermal amplification (RT-LAMP) was developed here for detection and …

A triple-target reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid and accurate detection of SARS-CoV-2 virus

C Zhang, J Lv, Y Cao, X Yao, M Yin, S Li, J Zheng… - Analytica Chimica …, 2023 - Elsevier
The spreading of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) across
the world has impacted people's health and lives worldwide in recent years. Rapid and …

[HTML][HTML] Rapid detection of SARS-CoV-2 using duplex reverse transcription-multienzyme isothermal rapid amplification in a point-of-care testing

H Chen, C Sun, Y Wang, X Gao, J You, W Yu… - Frontiers in Cellular …, 2021 - frontiersin.org
In December 2019, a severe acute respiratory syndrome caused by SARS-CoV-2 spread
rapidly worldwide. Portable nucleic acid tests of SARS-CoV-2 are critically important for …

[HTML][HTML] A high-throughput, multi-index isothermal amplification platform for rapid detection of 19 types of common respiratory viruses including SARS-CoV-2

W Xing, Y Liu, H Wang, S Li, Y Lin, L Chen, Y Zhao… - Engineering, 2020 - Elsevier
Fast and accurate diagnosis and the immediate isolation of patients infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are regarded as the most effective …

A Single-Tube Colorimetric Loop-Mediated Isothermal Amplification for Rapid Detection of SARS-CoV-2 RNA

S Hongjaisee, N Kham-Kjing, P Musikul… - Diagnostics, 2023 - mdpi.com
Since SARS-CoV-2 is a highly transmissible virus, a rapid and accurate diagnostic method
is necessary to prevent virus spread. We aimed to develop and evaluate a new rapid …

Multiplexed detection of respiratory pathogens with a portable analyzer in a “raw-sample-in and answer-out” manner

N Li, M Shen, J Liu, L Zhang, H Wang, Y Xu… - Microsystems & …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) has emerged, rapidly spread and caused
significant morbidity and mortality worldwide. There is an urgent public health need for rapid …

Rapid COVID-19 molecular diagnostic system using virus enrichment platform

YO Jang, HJ Lee, B Koo, HH Cha, JS Kwon, JY Kim… - Biosensors, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, is rapidly spreading and severely …

A novel reverse transcription loop-mediated isothermal amplification method for rapid detection of SARS-CoV-2

R Lu, X Wu, Z Wan, Y Li, X Jin, C Zhang - International Journal of …, 2020 - mdpi.com
COVID-19 has become a major global public health burden, currently causing a rapidly
growing number of infections and significant morbidity and mortality around the world. Early …