Despite its major role in complex human functions across the lifespan, most notably navigation, learning and memory, much of the genetic architecture of the hippocampal …
The hippocampus is composed of distinct subfields linked to diverse functions and disorders. The subfields can be mapped using high‐resolution magnetic resonance images …
Volumetric variations of the human brain are heritable and are associated with many brain- related complex traits. Here we performed genome-wide association studies (GWAS) of 101 …
The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in …
Identifying genetic variants influencing human brain structures may reveal new biological mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
SJ van Der Lee, MJ Knol, G Chauhan… - Communications …, 2019 - nature.com
Brain lobar volumes are heritable but genetic studies are limited. We performed genome- wide association studies of frontal, occipital, parietal and temporal lobe volumes in 16,016 …
Adult neurogenesis occurs in the dentate gyrus of the hippocampus during adulthood and contributes to sustaining the hippocampal formation. To investigate whether neurogenesis …
Aging is associated with reductions in hippocampal volume that are accelerated by Alzheimer's disease and vascular risk factors. Our genome-wide association study (GWAS) …
Background Variation in hippocampal volume has been linked to significant differences in memory, behavior, and cognition among individuals. To identify genetic variants underlying …