In vitro effect of Withania somnifera, AYUSH-64, and remdesivir on the activity of CYP-450 enzymes: Implications for possible herb−drug interactions in the …

SS Kasarla, SP Borse, Y Kumar, N Sharma… - Frontiers in …, 2022 - frontiersin.org
Ayurvedic medicines Withania somnifera Dunal (ashwagandha) and AYUSH-64 have been
used for the prevention and management of COVID-19 in India. The present study explores …

Pharmacokinetics and metabolism of traditional Chinese medicine in the treatment of COVID-19

X Xu, Q Shen, H Wang, Z Zeng, M Liu… - Current Drug …, 2022 - ingentaconnect.com
Background: The outbreak of coronavirus disease 19 (COVID-19) has caused great concern
to public health. Convincing clinical experiences showed that traditional Chinese medicine …

Role of cytochrome P450 2C9 in COVID-19 treatment: current status and future directions

SYM Lim, B Al Bishtawi, W Lim - European Journal of Drug Metabolism …, 2023 - Springer
The major human liver drug metabolising cytochrome P450 (CYP) enzymes are
downregulated during inflammation and infectious disease state, especially during …

Pharmacological Perspectives of Ayurvedic Herbs viz. Alstonia scholaris L., Picrorhiza kurroa, Swertia chirata and Caesalpinia crista Against COVID-19: A Mini …

V Kumar, SB Singh, S Singh - Mini-Reviews in Organic …, 2021 - ingentaconnect.com
Pandemic, COVID-19 came into existence in late December 2019 at Wuhan, China. To cure
the COVID-19 and reduction in morbidity, the development of potential vaccines and …

[HTML][HTML] Anti-COVID-19 drug candidates: A review on potential biological activities of natural products in the management of new coronavirus infection

A Prasansuklab, A Theerasri, P Rangsinth… - Journal of Traditional …, 2021 - Elsevier
Background and aim The novel coronavirus disease (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is now become a worldwide pandemic …

[HTML][HTML] Ayurvedic formulations: Potential COVID-19 therapeutics?

AAM Ali, A Bugarcic, N Naumovski, R Ghildyal - Phytomedicine Plus, 2022 - Elsevier
Abstract Background: While Molnupiravir and Paxlovid have recently been approved for use
in some countries, there are no widely available treatments for COVID-19, the disease …

Inhibition of drug-metabolizing enzymes by Qingfei Paidu decoction: Implication of herb-drug interactions in COVID-19 pharmacotherapy

F Zhang, J Huang, W Liu, CR Wang, YF Liu… - Food and Chemical …, 2021 - Elsevier
Abstract Corona Virus Disease 2019 (COVID-19) has spread all over the world and brings
significantly negative effects on human health. To fight against COVID-19 in a more efficient …

[HTML][HTML] Evaluation of potency of the selected bioactive molecules from Indian medicinal plants with MPro of SARS-CoV-2 through in silico analysis

P Halder, U Pal, P Paladhi, S Dutta, P Paul… - Journal of Ayurveda and …, 2022 - Elsevier
Background The recent outbreak of the novel SARS-CoV-2 across the globe and the
absence of specific drug against this virus lead the scientific community to look into some …

Herbal medicines to fight against COVID-19: new battle with an old weapon

RK Harwansh, S Bahadur - Current Pharmaceutical …, 2022 - ingentaconnect.com
The world population has suffered as a result of the COVID-19 pandemic. The disease has
become life-threatening in a very short time, harming citizens and the economic systems …

[HTML][HTML] Withania somnifera (L.) Dunal: opportunity for clinical repurposing in COVID-19 management

A Saggam, K Limgaokar, S Borse… - Frontiers in …, 2021 - frontiersin.org
As the COVID-19 pandemic is progressing, the therapeutic gaps in conventional
management have highlighted the need for the integration of traditional knowledge systems …