[HTML][HTML] The intersection of obesity and (long) COVID-19: Hypoxia, thrombotic inflammation, and vascular endothelial injury

M Xiang, X Wu, H Jing, VA Novakovic… - Frontiers in …, 2023 - frontiersin.org
The role of hypoxia, vascular endothelial injury, and thrombotic inflammation in worsening
COVID-19 symptoms has been generally recognized. Damaged vascular endothelium plays …

Obesity-related inflammation and endothelial dysfunction in COVID-19: Impact on disease severity

A De Lorenzo, V Estato… - Journal of …, 2021 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic has put into evidence another
pandemic–obesity. Currently, several studies have documented the association between …

[HTML][HTML] Endotheliitis and endothelial dysfunction in patients with COVID-19: its role in thrombosis and adverse outcomes

W Mosleh, K Chen, SE Pfau, A Vashist - Journal of Clinical Medicine, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV2), emerging in Wuhan, China and …

[HTML][HTML] Obesity as a risk factor for severe COVID-19 and complications: a review

F Demeulemeester, K de Punder, M van Heijningen… - Cells, 2021 - mdpi.com
Emerging data suggest that obesity is a major risk factor for the progression of major
complications such as acute respiratory distress syndrome (ARDS), cytokine storm and …

Obesity is a risk factor for severe COVID-19 infection: multiple potential mechanisms

N Sattar, IB McInnes, JJV McMurray - Circulation, 2020 - Am Heart Assoc
Circulation. 2020; 142: 4–6. DOI: 10.1161/CIRCULATIONAHA. 120.047659 July 7, 2020 5
certain ethnicities, eg, Asians. 1 Asians often display lower cardiorespiratory fitness and …

[HTML][HTML] Severe COVID-19 infection associated with endothelial dysfunction induces multiple organ dysfunction: a review of therapeutic interventions

Y Matsuishi, BJ Mathis, N Shimojo, J Subrina, N Okubo… - Biomedicines, 2021 - mdpi.com
Since December 2019, the SARS-CoV-2 (COVID-19) pandemic has transfixed the medical
world. COVID-19 symptoms vary from mild to severe and underlying chronic conditions such …

Obesity and COVID-19: immune and metabolic derangement as a possible link to adverse clinical outcomes

E Korakas, I Ikonomidis… - American Journal …, 2020 - journals.physiology.org
Recent reports have shown a strong association between obesity and the severity of COVID-
19 infection, even in the absence of other comorbidities. After infecting the host cells, severe …

[HTML][HTML] Long COVID 19 syndrome: is it related to microcirculation and endothelial dysfunction? Insights from TUN-EndCOV study

S Charfeddine, H Ibn Hadj Amor, J Jdidi… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 disease is a multisystem disease due to in part to the vascular endothelium
injury. Lasting effects and long-term sequalae could persist after the infection and may be …

COVID-19 and cardiovascular consequences: Is the endothelial dysfunction the hardest challenge?

S Del Turco, A Vianello, R Ragusa, C Caselli… - Thrombosis Research, 2020 - Elsevier
Abstract A Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has become
a pandemic disease named Coronavirus Disease-19 (COVID-19) of epochal dimension …

[HTML][HTML] Hypercoagulopathy and adipose tissue exacerbated inflammation may explain higher mortality in COVID-19 patients with obesity

G Pasquarelli-do-Nascimento… - Frontiers in …, 2020 - frontiersin.org
COVID-19, caused by SARS-CoV-2, is characterized by pneumonia, lymphopenia,
exhausted lymphocytes and a cytokine storm. Several reports from around the world have …