Distinct skeletal muscle gene regulation from active contraction, passive vibration, and whole body heat stress in humans

MA Petrie, AL Kimball, CL McHenry, M Suneja, CL Yen… - PloS one, 2016 - journals.plos.org
Skeletal muscle exercise regulates several important metabolic genes in humans. We know
little about the effects of environmental stress (heat) and mechanical stress (vibration) on …

Skeletal muscle signaling following whole-body and localized heat exposure in humans

M Ihsan, L Deldicque, J Molphy, F Britto… - Frontiers in …, 2020 - frontiersin.org
This study identified the changes in hypertrophy/atrophy and mitochondrial-related signaling
in human skeletal muscle following whole-body (WB) and localized single leg (SL) heat …

[HTML][HTML] Adaptations of mouse skeletal muscle to low intensity vibration training

JN McKeehen, SA Novotny, KA Baltgalvis… - Medicine and science …, 2013 - ncbi.nlm.nih.gov
Purpose We tested the hypothesis that low intensity vibration training in mice improves
contractile function of hindlimb skeletal muscles and promotes exercise-related cellular …

The heat shock connection: skeletal muscle hypertrophy and atrophy

ZJ Fennel, FT Amorim, MR Deyhle… - American Journal …, 2022 - journals.physiology.org
Skeletal muscle is an integral tissue system that plays a crucial role in the physical function
of all vertebrates and is a key target for maintaining or improving health and performance …

Vibration mechanosignals superimposed to resistive exercise result in baseline skeletal muscle transcriptome profiles following chronic disuse in bed rest

M Salanova, G Gambara, M Moriggi, M Vasso… - Scientific reports, 2015 - nature.com
Disuse-induced muscle atrophy is a major concern in aging, in neuromuscular diseases,
post-traumatic injury and in microgravity life sciences affecting health and fitness also of …

Single-cell sequencing deconvolutes cellular responses to exercise in human skeletal muscle

A Lovrić, A Rassolie, S Alam, M Mandić, A Saini… - Communications …, 2022 - nature.com
Skeletal muscle adaptations to exercise have been associated with a range of health-related
benefits, but cell type-specific adaptations within the muscle are incompletely understood …

The dawn of the functional genomics era in muscle physiology

RAE Seaborne, J Ochala - The Journal of Physiology, 2023 - Wiley Online Library
Skeletal muscle is the most abundant component of the mature mammalian phenotype.
Designed to generate contractile force and movement, skeletal muscle is crucial for …

Exercise-induced skeletal muscle signaling pathways and human athletic performance

DM Camera, WJ Smiles, JA Hawley - Free Radical Biology and Medicine, 2016 - Elsevier
Skeletal muscle is a highly malleable tissue capable of altering its phenotype in response to
external stimuli including exercise. This response is determined by the mode,(endurance …

Transcriptome response of human skeletal muscle to divergent exercise stimuli

JM Dickinson, AC D'Lugos… - Journal of Applied …, 2018 - journals.physiology.org
Aerobic (AE) and resistance exercise (RE) elicit unique adaptations in skeletal muscle that
have distinct implications for health and performance. The purpose of this study was to …

Signaling pathways in skeletal muscle remodeling

R Bassel-Duby, EN Olson - Annu. Rev. Biochem., 2006 - annualreviews.org
Skeletal muscle is comprised of heterogeneous muscle fibers that differ in their physiological
and metabolic parameters. It is this diversity that enables different muscle groups to provide …