Formulation of nanospanlastics as a promising approach for‎ improving the topical delivery of a natural leukotriene inhibitor (3-‎ acetyl-11-keto-β-boswellic acid) …

F Badria, E Mazyed - Drug design, development and therapy, 2020 - Taylor & Francis
Purpose The current study aimed to discuss the potential of nanospanlastics as a surfactant-
based vesicular system for improving the topical delivery of 3-acetyl-11-keto-β-boswellic …

Optimization of nanostructured lipid carriers for topical delivery of nimesulide using Box–Behnken design approach

SMM Moghddam, A Ahad, M Aqil… - Artificial cells …, 2017 - Taylor & Francis
Objective: The aim of the present study was to develop and optimize topically applied
nimesulide-loaded nanostructured lipid carriers. Materials and methods: Box–Behnken …

Nanostructured gel for topical delivery of azelaic acid: Designing, characterization, and in-vitro evaluation

DS Malik, G Kaur - Journal of Drug Delivery Science and Technology, 2018 - Elsevier
The study is designed to formulate, optimize and evaluate Azelaic acid loaded nano-
structured lipid carrier (NLCs) with an aim to enhance its skin targeting, retention, and …

Voriconazole loaded nanostructured lipid carriers based topical delivery system: QbD based designing, characterization, in-vitro and ex-vivo evaluation

T Waghule, VK Rapalli, G Singhvi, P Manchanda… - Journal of drug delivery …, 2019 - Elsevier
Clinical investigation showed that voriconazole exhibits various adverse effects such as
nausea, vomiting, and other gastric disturbances. To overcome these associated side …

Application of Box–Behnken design for preparation of glibenclamide loaded lipid based nanoparticles: Optimization, in vitro skin permeation, drug release and in vivo …

M Aslam, M Aqil, A Ahad, AK Najmi, Y Sultana… - Journal of Molecular …, 2016 - Elsevier
The objective of the present study was to develop nanostructured lipid carrier (NLC) for
enhanced transdermal delivery of glibenclamide. The NLC of glibenclamide was prepared …

Development characterization and skin permeating potential of lipid based novel delivery system for topical treatment of psoriasis

M Pradhan, D Singh, MR Singh - Chemistry and physics of lipids, 2015 - Elsevier
The aim of this study was to develop, optimize and evaluate the potential of solid lipid
nanoparticles (SLNs) as a topical delivery system for targeted and prolonged release of …

Ultra-deformable free fatty acid based nano-carriers for topical delivery of Luteolin: A potential paradigm for management of Methicillin-Resistant Staphylococcus …

MY Zakaria, WA Eraqi, SA Mohamed - International Journal of …, 2023 - Elsevier
The incidences of antimicrobial resistance in particular, Methicillin-Resistant Staphylococcus
aureus (MRSA) have increased during the last two decades. However, conventional dosage …

Development of solid lipid nanoparticles based controlled release system for topical delivery of terbinafine hydrochloride

H Vaghasiya, A Kumar, K Sawant - European journal of pharmaceutical …, 2013 - Elsevier
The study describes the development and evaluation of solid lipid nanoparticles (SLNs) of
terbinafine hydrochloride (TH) for sustained release and skin targeting. TH-loaded SLNs …

Formulation and optimization of topical solid lipid nanoparticles based gel of dapsone using design of experiment

SS Deshkar, SG Bhalerao, MS Jadhav… - Pharmaceutical …, 2018 - ingentaconnect.com
Objective: The present research work was designed to formulate and evaluate solid lipid
nanoparticles (SLN) loaded gel of Dapsone (DS). An attempt was made to develop topical …

Topical Delivery of Fenoprofen Calcium via Elastic Nano-vesicular Spanlastics: Optimization Using Experimental Design and In Vivo Evaluation

DA Farghaly, AA Aboelwafa, MY Hamza… - AAPS PharmSciTech, 2017 - Springer
The aim of this study was to investigate the potential of surfactant-based nanovesicular
system (spanlastics) for topical delivery of fenoprofen calcium (FPCa) to eliminate its oral …