Effect of aerobic exercise as a treatment on type 2 diabetes mellitus with depression-like behavior zebrafish

L Wang, J Ma, W Wu, Y Fang, F Liu, Q Yang, X Hu… - Life Sciences, 2022 - Elsevier
Background Depression is the most known complication of type 2 diabetes mellitus (T2DM).
Aerobic exercise improves glycemic control in T2DM, although the underlying mechanisms …

Swimming exercise attenuates anxiety-like behavior by reducing brain oxidative stress in type 2 diabetic mice

P Matinfar, M Peeri, MA Azarbayjani - Physiology & Behavior, 2021 - Elsevier
Anxiety-related behaviors are among the most prevalent psychiatric disorders in patients
with type 2 diabetes (T2D). The protective effect of exercise on neuropsychiatric disorders …

Swimming exercise decreases depression‐like behaviour and inflammatory cytokines in a mouse model of type 2 diabetes

M Gilak‐Dalasm, M Peeri… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? Can swimming exercise decrease
depression‐like behaviour and inflammation in type 2 diabetic mice? What is the main …

High-glucose/high-cholesterol diet in zebrafish evokes diabetic and affective pathogenesis: The role of peripheral and central inflammation, microglia and apoptosis

JJ Wang, YJ Li, K Lai, QM Zhong, KA Demin… - Progress in Neuro …, 2020 - Elsevier
Neuroinflammation and metabolic deficits contribute to the etiology of human affective
disorders, such as anxiety and depression. The zebrafish (Danio rerio) has recently …

Metabolic factors-triggered inflammatory response drives antidepressant effects of exercise in CUMS rats

W Liu, H Wang, Y Wang, H Li, L Ji - Psychiatry research, 2015 - Elsevier
Chronic stress is a potential contributing factor for depression, accompanying with metabolic
and inflammatory response. Exercise is considered as a treatment for depression, but …

Swimming exercise ameliorates depressive-like behavior by anti-inflammation activity, rebalancing gut Escherichia coli and Lactobacilli

Z Ding, L Du - Brain Research, 2022 - Elsevier
Major depressive disorder (MDD) is a common mental disease with high morbidity,
recurrence and mortality and is a serious global health problem. Aerobic exercise produces …

Regular exercise cures depression-like behavior via VEGF-Flk-1 signaling in chronically stressed mice

T Kiuchi, H Lee, T Mikami - Neuroscience, 2012 - Elsevier
In animals, chronic stress leads to the development of depression-like behavior and
decreases neurogenesis and blood vessel density in hippocampus, whereas …

Treadmill exercise training alleviates diabetes-induced depressive-like behavior and cognitive impairment by improving hippocampal CA1 neurons injury in db/db …

Z Zhou, M Wang, C Huang, Y Li, L Gao, Y Zhu… - Brain Research …, 2022 - Elsevier
Patients with diabetes mellitus (DM) have an increased risk of diabetic encephalopathy
symptoms such as depressive-like behaviour and cognitive impairment. Exercise is an …

[HTML][HTML] Neuroprotective effects of treadmill exercise on BDNF and PI3-K/Akt signaling pathway in the cortex of transgenic mice model of Alzheimer's disease

JH Koo, IS Kwon, EB Kang, CK Lee… - Journal of exercise …, 2013 - ncbi.nlm.nih.gov
Abstract (AD). Although physical exercise and AD have received attention in the scientific
literature, the mechanism through which treadmill exercise may impact the brain insulin …

[HTML][HTML] The effects of exercise and diet on mental status, insulin signaling pathway, and microbiome in obese mice

SS Park, TW Kim, BK Kim, SH Kim… - Journal of Exercise …, 2022 - ncbi.nlm.nih.gov
The aim of this study was to investigate the effects of exercise and diet on mental status,
insulin signaling pathway, serotonin synthesis, and microbiome in high-fat-induced obesity …