Abstract Purpose of Review To provide an updated summary of discoveries made to date
resulting from genome-wide association study (GWAS) and sequencing studies, and to …

Genetic studies have identified> 60 loci associated with the risk of developing type 1
diabetes (T1D). The vast majority of these are identified by genome‐wide association …

Type 1 Diabetes (T1D) is a chronic multifactorial disease with a strong genetic component,
which, through interactions with specific environmental factors, triggers disease onset. T1D …

Starting with early crucial discoveries of the role of the major histocompatibility complex,
genetic studies have long had a role in understanding the biology of type 1 diabetes (T1D) …

Despite numerous candidate gene and linkage studies, the field of type 2 diabetes (T2D)
genetics had until recently succeeded in identifying few genuine disease-susceptibility loci …

Abstract Type 1 diabetes (T1D) is a multifactorial disease resulting from an immune-
mediated destruction of the insulin-producing pancreatic β cells. Several environmental and …

Type 2 diabetes mellitus has been at the forefront of human diseases and phenotypes
studied by new genetic analyses. Thanks to genome‐wide association studies, we have …

Over the past two years, there has been a spectacular change in the capacity to identify
common genetic variants that contribute to predisposition to complex multifactorial …

Type 1 diabetes mellitus (T1D) is a complex autoimmune disorder characterised by loss of
the insulin-producing pancreatic beta cells in genetically predisposed individuals, ultimately …

Genome-wide association studies (GWAS) have facilitated a substantial and rapid rise in the
number of confirmed genetic susceptibility variants for type 2 diabetes (T2D). Approximately …