Type II restriction endonucleases—a historical perspective and more

A Pingoud, GG Wilson, W Wende - Nucleic acids research, 2014 - academic.oup.com
This article continues the series of Surveys and Summaries on restriction endonucleases
(REases) begun this year in Nucleic Acids Research. Here we discuss 'Type II'REases, the …

Type II restriction endonucleases: structure and mechanism

A Pingoud, M Fuxreiter, V Pingoud… - Cellular and molecular life …, 2005 - Springer
Type II restriction endonucleases are components of restriction modification systems that
protect bacteria and archaea against invading foreign DNA. Most are homodimeric or …

Type I restriction enzymes and their relatives

WAM Loenen, DTF Dryden, EA Raleigh… - Nucleic acids …, 2014 - academic.oup.com
Type I restriction enzymes (REases) are large pentameric proteins with separate restriction
(R), methylation (M) and DNA sequence-recognition (S) subunits. They were the first …

Structure and function of type II restriction endonucleases

A Pingoud, A Jeltsch - Nucleic acids research, 2001 - academic.oup.com
More than 3000 type II restriction endonucleases have been discovered. They recognize
short, usually palindromic, sequences of 4–8 bp and, in the presence of Mg2+, cleave the …

[HTML][HTML] Many type IIs restriction endonucleases interact with two recognition sites before cleaving DNA

AJ Bath, SE Milsom, NA Gormley, SE Halford - Journal of Biological …, 2002 - ASBMB
Type IIs restriction endonucleases recognize asymmetric DNA sequences and cleave both
DNA strands at fixed positions, typically several base pairs away from the recognition site …

Restriction and modification enzymes and their recognition sequences

RJ Roberts - Gene, 1980 - Elsevier
Gene, 8 (1980 329--343 329 o Elsevier/North-Holland Biomedical Press Review RESTRICTION
AND MODIFICATION ENZYMES AND THEIR RECOG Page 1 Gene, 8 (1980 329--343 329 o …

Recognition and cleavage of DNA by type‐II restriction endonucleases

A Pingoud, A Jeltsch - European Journal of Biochemistry, 1997 - Wiley Online Library
Restriction endonucleases are enzymes which recognize short DNA sequences and cleave
the DNA in both strands. Depending on the enzymological properties different types are …

Highlights of the DNA cutters: a short history of the restriction enzymes

WAM Loenen, DTF Dryden, EA Raleigh… - Nucleic acids …, 2014 - academic.oup.com
Abstract In the early 1950's,'host-controlled variation in bacterial viruses' was reported as a
non-hereditary phenomenon: one cycle of viral growth on certain bacterial hosts affected the …

Restriction endonuclease: Classification, properties, and applications

RJ Williams - Molecular biotechnology, 2003 - Springer
Restriction endonucleases have become a fundamental tool of molecular biology with many
commercial vendors and extensive product lines. While a significant amount has been …

Structure and function of restriction endonucleases

AK Aggarwal - Current opinion in structural biology, 1995 - Elsevier
Structures of two restriction endonucleases, BamHI and PvuII, were reported in the past
year. This doubles the number of restriction endonuclease structures now known from two to …