Redox regulation of cardiovascular inflammation–Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species

P Wenzel, S Kossmann, T Münzel, A Daiber - Free Radical Biology and …, 2017 - Elsevier
Oxidative stress is a major hallmark of cardiovascular diseases although a causal link was
so far not proven by large clinical trials. However, there is a close association between …

Oxidative stress and inflammation in heart disease: do antioxidants have a role in treatment and/or prevention?

FJ Pashkow - International journal of inflammation, 2011 - Wiley Online Library
Inflammation triggered by oxidative stress is the cause of much, perhaps even most, chronic
human disease including human aging. The oxidative stress originates mainly in …

[HTML][HTML] Antioxidants, inflammation and cardiovascular disease

H Mangge, K Becker, D Fuchs… - World journal of …, 2014 - ncbi.nlm.nih.gov
Multiple factors are involved in the etiology of cardiovascular disease (CVD). Pathological
changes occur in a variety of cell types long before symptoms become apparent and …

[HTML][HTML] The role of reactive oxygen species in the pathophysiology of cardiovascular diseases and the clinical significance of myocardial redox

D Moris, M Spartalis, E Spartalis… - Annals of …, 2017 - ncbi.nlm.nih.gov
Acute and chronic excessive intracellular increase of reactive oxygen species (ROS) is
involved in the development and progression of cardiovascular diseases. ROS are by …

The cooperative roles of inflammation and oxidative stress in the pathogenesis of hypertension

SD Crowley - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Innate and adaptive immunity play fundamental roles in the development of
hypertension and its complications. As effectors of the cell-mediated immune response …

Vascular inflammation and oxidative stress: major triggers for cardiovascular disease

S Steven, K Frenis, M Oelze, S Kalinovic… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

Oxidative stress in ischemic heart disease

A Kibel, AM Lukinac, V Dambic, I Juric… - Oxidative medicine …, 2020 - Wiley Online Library
One of the novel interesting topics in the study of cardiovascular disease is the role of the
oxidation system, since inflammation and oxidative stress are known to lead to …

Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling

I Andreadou, A Daiber, GF Baxter, MF Brizzi… - Free Radical Biology …, 2021 - Elsevier
The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …

Angiotensin II-induced production of mitochondrial reactive oxygen species: potential mechanisms and relevance for cardiovascular disease

SI Dikalov, RR Nazarewicz - Antioxidants & redox signaling, 2013 - liebertpub.com
Significance: The role of reactive oxygen species (ROS) in angiotensin II (AngII) induced
endothelial dysfunction, cardiovascular and renal remodeling, inflammation, and fibrosis has …

[HTML][HTML] Inflammation in metabolic and cardiovascular disorders—role of oxidative stress

Y Sun, E Rawish, HM Nording, HF Langer - Life, 2021 - mdpi.com
Cardiovascular diseases (CVD) constitute the main cause of death worldwide. Both
inflammation and oxidative stress have been reported to be involved in the progress of CVD …