Advances in sarcopenia: mechanisms, therapeutic targets, and intervention strategies

Y Zheng, J Feng, Y Yu, M Ling, X Wang - Archives of Pharmacal Research, 2024 - Springer
Sarcopenia is a multifactorial condition characterized by loss of muscle mass. It poses
significant health risks in older adults worldwide. Both pharmacological and non …

[HTML][HTML] Pharmacological interventions for treatment of sarcopenia: current status of drug development for sarcopenia

JY Kwak, KS Kwon - Annals of geriatric medicine and research, 2019 - ncbi.nlm.nih.gov
Sarcopenia, the loss of skeletal muscle mass and function with age, was first recognized as
a disease in the International Classification of Diseases, Tenth Revision, Clinical …

Advances in research on pharmacotherapy of sarcopenia

Y Feike, L Zhijie, C Wei - Aging Medicine, 2021 - Wiley Online Library
Sarcopenia is a comprehensive degenerative disease with the progressive loss of skeletal
muscle mass with age, accompanied by the loss of muscle strength and muscle dysfunction …

Current pharmacotherapies for sarcopenia

JP Hardee, GS Lynch - Expert Opinion on Pharmacotherapy, 2019 - Taylor & Francis
Introduction: Sarcopenia, the age-related loss of skeletal muscle mass and function, is a
global health problem that contributes to the development of physical disability, morbidity …

The Future of Drugs in Sarcopenia

MB Zazzara, RS Penfold, G Onder - Sarcopenia: Research and Clinical …, 2021 - Springer
Sarcopenia is the age-related decline in muscle mass and strength and is associated with
increased risk of adverse health outcomes including falls, morbidity, loss of independence …

The Current Landscape of Pharmacotherapies for Sarcopenia

G Bahat, S Ozkok - Drugs & Aging, 2024 - Springer
Sarcopenia is a skeletal muscle disorder characterized by progressive and generalized
decline in muscle mass and function. Although it is mostly known as an age-related disorder …

Age is just a number: progress and obstacles in the discovery of new candidate drugs for sarcopenia

HJ Kim, DW Jung, DR Williams - Cells, 2023 - mdpi.com
Sarcopenia is a disease characterized by the progressive loss of skeletal muscle mass and
function that occurs with aging. The progression of sarcopenia is correlated with the onset of …

Sarcopenia: no consensus, no diagnostic criteria, and no approved indication—How did we get here?

WJ Evans, J Guralnik, P Cawthon, J Appleby, F Landi… - Geroscience, 2024 - Springer
In addition to the role of skeletal muscle in movement and locomotion, muscle plays a critical
role in a broad array of metabolic processes that can contribute to improved health or risk of …

Selecting potential pharmacological interventions in sarcopenia

AJ Kilsby, AA Sayer, MD Witham - Drugs & aging, 2017 - Springer
Sarcopenia of age is prevalent and costly and proven pharmacological interventions are
currently lacking. The pathophysiology of sarcopenia is incompletely understood but …

Understanding of sarcopenia: from definition to therapeutic strategies

JW Kim, R Kim, H Choi, SJ Lee, GU Bae - Archives of pharmacal research, 2021 - Springer
Sarcopenia refers to the gradual loss of skeletal muscle mass and function along with aging
and is a social burden due to growing healthcare cost associated with a super-aging society …