Polystyrene nanoparticles internalization in human gastric adenocarcinoma cells

M Forte, G Iachetta, M Tussellino, R Carotenuto… - Toxicology in Vitro, 2016 - Elsevier
The increase in the use of nanoparticles, as a promising tool for drug delivery or as a food
additive, raises questions about their interaction with biological systems, especially in terms …

Energy independent uptake and release of polystyrene nanoparticles in primary mammalian cell cultures

I Fiorentino, R Gualtieri, V Barbato, V Mollo… - Experimental cell …, 2015 - Elsevier
Nanoparticle (NPs) delivery systems in vivo promises to overcome many obstacles
associated with the administration of drugs, vaccines, plasmid DNA and RNA materials …

Evaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitro

HJ Johnston, M Semmler-Behnke, DM Brown… - Toxicology and applied …, 2010 - Elsevier
Nanoparticles (NPs) are being used within diverse applications such as medicines, clothing,
cosmetics and food. In order to promote the safe development of such nanotechnologies it is …

Effects of transport inhibitors on the cellular uptake of carboxylated polystyrene nanoparticles in different cell lines

T Dos Santos, J Varela, I Lynch, A Salvati, KA Dawson - PloS one, 2011 - journals.plos.org
Nanotechnology is expected to play a vital role in the rapidly developing field of
nanomedicine, creating innovative solutions and therapies for currently untreatable …

Uptake and bio-reactivity of polystyrene nanoparticles is affected by surface modifications, ageing and LPS adsorption: in vitro studies on neural tissue cells

K Murali, Y Li, K Demeter, Z Környei, E Madarász - Nanoscale, 2015 - pubs.rsc.org
Because of their capacity of crossing an intact blood–brain barrier and reaching the brain
through an injured barrier or via the nasal epithelium, nanoparticles have been considered …

The effect of nanoparticle uptake on cellular behavior: disrupting or enabling functions?

A Panariti, G Miserocchi, I Rivolta - Nanotechnology, science and …, 2012 - Taylor & Francis
Nanoparticles (NPs) are materials with overall dimensions in the nanoscale range. They
have unique physicochemical properties, and have emerged as important players in current …

Nanoparticles: cellular uptake and cytotoxicity

IM Adjei, B Sharma, V Labhasetwar - Nanomaterial: impacts on cell …, 2014 - Springer
Understanding the interactions of nanoparticles (NPs) with cells and how these interactions
influence their cellular uptake is essential to exploring the biomedical applications of NPs …

Surface charge-dependent cellular uptake of polystyrene nanoparticles

S Jeon, J Clavadetscher, DK Lee, SV Chankeshwara… - Nanomaterials, 2018 - mdpi.com
The evaluation of the role of physicochemical properties in the toxicity of nanoparticles is
important for the understanding of toxicity mechanisms and for controlling the behavior of …

Toxicity of commercially available engineered nanoparticles to Caco-2 and SW480 human intestinal epithelial cells

TE Abbott Chalew, KJ Schwab - Cell biology and toxicology, 2013 - Springer
The effects of ingestion of engineered nanoparticles (NPs), especially via drinking water, are
unknown. Using NPs spiked into synthetic water and cell culture media, we investigated cell …

In vitro gastrointestinal digestion increases the translocation of polystyrene nanoparticles in an in vitro intestinal co-culture model

AP Walczak, E Kramer, PJM Hendriksen… - …, 2015 - Taylor & Francis
The conditions of the gastrointestinal tract may change the physicochemical properties of
nanoparticles (NPs) and therewith the bioavailability of orally taken NPs. Therefore, we …