Y Zhao, L Gan, L Ren, Y Lin, C Ma, X Lin - Brain research, 2022 - Elsevier
The blood-brain barrier (BBB) is a dynamic structure that protects the brain from harmful blood-borne, endogenous and exogenous substances and maintains the homeostatic …
BW Chow, C Gu - Trends in neurosciences, 2015 - cell.com
The blood–brain barrier (BBB) maintains the optimal microenvironment in the central nervous system (CNS) for proper brain function. The BBB comprises specialized CNS …
J Maiuolo, M Gliozzi, V Musolino, M Scicchitano… - International journal of …, 2018 - mdpi.com
The main neurovascular unit of the Blood Brain Barrier (BBB) consists of a cellular component, which includes endothelial cells, astrocytes, pericytes, microglia, neurons, and …
The blood–brain barrier (BBB) is the specialized system of brain microvascular endothelial cells (BMVEC) that shields the brain from toxic substances in the blood, supplies brain …
FL Cardoso, D Brites, MA Brito - Brain research reviews, 2010 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the central nervous system that strictly controls the exchanges between the blood and brain …
C Yang, KE Hawkins, S Doré… - American Journal of …, 2019 - journals.physiology.org
As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …
M Blanchette, R Daneman - Mechanisms of development, 2015 - Elsevier
The central nervous system (CNS) is vascularized by a dense capillary network that is critical to deliver oxygen and nutrients, and remove carbon dioxide and waste products, from …
F Takata, S Nakagawa, J Matsumoto… - Frontiers in cellular …, 2021 - frontiersin.org
Neuroinflammation is involved in the onset or progression of various neurodegenerative diseases. Initiation of neuroinflammation is triggered by endogenous substances (damage …
MA Petty, EH Lo - Progress in neurobiology, 2002 - Elsevier
A wide range of central nervous system (CNS) disorders include neuroinflammatory events that perturb blood–brain barrier (BBB) integrity. Mechanisms by which the BBB responds to …