Brain structure relations with psychopathology trajectories in the ABCD study

AL Romer, B Ren, DA Pizzagalli - Journal of the American Academy of …, 2023 - Elsevier
Objective A general psychopathology (p) factor captures shared variation across mental
disorders. Structural neural alterations have been associated with the p factor concurrently …

The relationship between brain structure and general psychopathology in preadolescents

L Mewton, B Lees, LM Squeglia… - Journal of Child …, 2022 - Wiley Online Library
Background An emerging body of literature has indicated that broad, transdiagnostic
dimensions of psychopathology are associated with alterations in brain structure across the …

[HTML][HTML] Identifying profiles of brain structure and associations with current and future psychopathology in youth

M Mattoni, S Wilson, TM Olino - Developmental Cognitive Neuroscience, 2021 - Elsevier
Brain structure is often studied as a marker of youth psychopathology by examining
associations between volume or thickness of individual regions and specific diagnoses …

Neurobiological clusters are associated with trajectories of overall psychopathology in youth

C Wang, R Hayes, K Roeder, M Jalbrzikowski - Biological Psychiatry …, 2023 - Elsevier
Background Integrating multiple neuroimaging modalities to identify clusters of individuals
and then associating these clusters with psychopathology is a promising approach for …

[HTML][HTML] Dimensions of psychopathology are dissociably linked to brain structure in youth

AN Kaczkurkin, SS Park, A Sotiras… - The American journal …, 2019 - ncbi.nlm.nih.gov
Objective: High comorbidity among psychiatric disorders suggests that they may share
underlying neurobiological deficits. Abnormalities in cortical thickness and volume have …

Brain morphometry points to emerging patterns of psychosis, depression, and anxiety vulnerability over a 2-year period in childhood

TG Vargas, VA Mittal - Psychological medicine, 2023 - cambridge.org
Background Gray matter morphometry studies have lent seminal insights into the etiology of
mental illness. Existing research has primarily focused on adults and then, typically on a …

Transdiagnostic dimensions of psychopathology explain individuals' unique deviations from normative neurodevelopment in brain structure

L Parkes, TM Moore, ME Calkins, PA Cook… - Translational …, 2021 - nature.com
Psychopathology is rooted in neurodevelopment. However, clinical and biological
heterogeneity, together with a focus on case-control approaches, have made it difficult to link …

Evidence for dissociable linkage of dimensions of psychopathology to brain structure in youths

AN Kaczkurkin, SS Park, A Sotiras… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: High comorbidity among psychiatric disorders suggests that they may share
underlying neurobiological deficits. Abnormalities in cortical thickness and volume have …

Neural signatures of data-driven psychopathology dimensions at the transition to adolescence

A Modabbernia, G Michelini, A Reichenberg… - European …, 2022 - cambridge.org
Background One of the challenges in human neuroscience is to uncover associations
between brain organization and psychopathology in order to better understand the …

Tracking brain development and dimensional psychiatric symptoms in children: a longitudinal population-based neuroimaging study

RL Muetzel, LME Blanken… - American Journal of …, 2018 - Am Psychiatric Assoc
Objective: Psychiatric symptomatology during childhood predicts persistent mental illness
later in life. While neuroimaging methodologies are routinely applied cross-sectionally to the …