M Tsalenchuk, SM Gentleman, SJ Marzi - npj Parkinson's Disease, 2023 - nature.com
Sporadic Parkinson's disease (PD) is a progressive neurodegenerative disease, with a complex risk structure thought to be influenced by interactions between genetic variants and …
HM Gao, JS Hong - Progress in neurobiology, 2011 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disease. The gradual, irreversible loss of dopamine neurons in the substantia nigra is the signature lesion …
Interactions between genetic factors and environmental exposures are thought to be major contributors to the etiology of Parkinson's disease. While such interactions are poorly …
L Polito, A Greco, D Seripa - Parkinson's disease, 2016 - Wiley Online Library
The discovery of causative mutations for Parkinson's disease (PD) as well as their functional characterization in cellular and animal models has provided crucial insight into the …
CA Ross, WW Smith - Parkinsonism & related disorders, 2007 - Elsevier
PD is the second most common neurodegenerative disease, and affects 5% of the population by the age of 85. PD is a multi-factorial disease with a complex etiology including …
Parkinson's disease (PD) is the second most common neurodegenerative disorder with an unclear etiology and no disease-modifying treatment to date. PD is considered a …
A Reynoso, R Torricelli, BM Jacobs, J Shi… - Annals of …, 2024 - Wiley Online Library
Objective Parkinson's disease (PD) is a neurodegenerative disorder with complex etiology. Multiple genetic and environmental factors have been associated with PD, but most PD risk …
Parkinson's disease (PD), a late‐onset neurodegenerative disorder, occurs most commonly in a “sporadic”(idiopathic) form, without a clearly defined genetic basis and only a vaguely …
Parkinson's disease (PD) is a heterogeneous neurodegenerative disorder that affects an estimated 10 million sufferers worldwide. The two forms of PD include familial and sporadic …