A growing body of evidence suggests that mechanical signals emanating from the cell's
microenvironment are fundamental regulators of cell behaviour. Moreover, at the …

Cell behaviour is strongly influenced by physical, mechanical contacts between cells and
their extracellular matrix. We review how the transcriptional regulators YAP and TAZ …

Biophysical cues, such as mechanical properties, play a critical role in tissue growth and
homeostasis. During organ development and tissue injury repair, compressive and tensional …

To perceive their three-dimensional environment, cells and tissues must be able to sense
and interpret various physical forces like shear, tensile, and compression stress. These …

Organ size is controlled by the concerted action of biochemical and physical processes.
Although mechanical forces are known to regulate cell and tissue behavior, as well as …

The physical and mechanical properties of the cellular microenvironment regulate cell
shape and can strongly influence cell fate. How mechanical cues are sensed and …

Skeletal muscle is not only translating chemical energy into mechanical work, it is also a
highly adaptive and regenerative tissue whose architecture and functionality is determined …

Cells perceive their microenvironment not only through soluble signals but also through
physical and mechanical cues, such as extracellular matrix (ECM) stiffness or confined …

The YAP/TAZ family of transcriptional co‐activators drives cell proliferation in epithelial
tissues and cancers. Yet, how YAP and TAZ are physiologically regulated remains unclear …

Innate immune cells are responsible for eliminating foreign infectious agents and cellular
debris, and their ability to perceive, respond to, and integrate biochemical and mechanical …