Zinc and the innovative zinc-α2-glycoprotein adipokine play an important role in lipid metabolism: a critical review

M Banaszak, I Górna, J Przysławski - Nutrients, 2021 - mdpi.com
Numerous studies indicate that zinc and the new zinc-related adipokine, zinc-α2-
glycoprotein (ZAG), are involved in lipid metabolism. Excess body fat lowers blood …

Role of zinc in zinc-α2-glycoprotein metabolism in obesity: a review of literature

JS Severo, JBS Morais, JB Beserra… - Biological trace element …, 2020 - Springer
Excessive adipose tissue promotes the manifestation of endocrine disorders such as
reduction of the secretion of zinc-α2-glycoprotein (ZAG), an adipokine with anti-inflammatory …

Zinc-alpha 2-glycoprotein gene expression in adipose tissue is related with insulin resistance and lipolytic genes in morbidly obese patients

L Garrido-Sanchez, E García-Fuentes… - PloS one, 2012 - journals.plos.org
Objective Zinc-α2 glycoprotein (ZAG) stimulates lipid loss by adipocytes and may be
involved in the regulation of adipose tissue metabolism. However, to date no studies have …

Lower zinc-α2-glycoprotein production by adipose tissue and liver in obese patients unrelated to insulin resistance

DM Selva, A Lecube, C Hernandez… - The Journal of …, 2009 - academic.oup.com
Context: Zinc-α2 glycoprotein (ZAG) has been proposed as a new candidate in the
pathogenesis of obesity, but most of the information stems from studies performed in rodents …

Zinc-α2-glycoprotein: an adipokine modulator of body fat mass?

C Bing, T Mracek, D Gao, P Trayhurn - International journal of obesity, 2010 - nature.com
The importance of white adipose tissue in the control of energy balance is now firmly
recognized. In addition to fuel storage, adipocytes secrete an array of proteins factors …

Serum zinc-α2-glycoprotein correlates with adiposity, triglycerides, and the key components of the metabolic syndrome in Chinese subjects

DCY Yeung, KSL Lam, Y Wang… - The Journal of Clinical …, 2009 - academic.oup.com
Context: Zinc-α2-glycoprotein (ZAG) is a 40-kDa circulating glycoprotein secreted from the
liver and adipose tissues. Animal studies have demonstrated the role of ZAG as a lipid …

Zinc-α2-glycoprotein is involved in regulation of body weight through inhibition of lipogenic enzymes in adipose tissue

FY Gong, SJ Zhang, JY Deng, HJ Zhu, H Pan… - International journal of …, 2009 - nature.com
Objective: To elucidate the association of serum ZAG level with body weight and percentage
of body fat in normal, obese subjects and high-fat diet (HFD)-induced obese mice. Design …

[HTML][HTML] Downregulation of zinc-α2-glycoprotein in adipose tissue and liver of obese ob/ob mice and by tumour necrosis factor-α in adipocytes

T Mracek, D Gao, T Tzanavari, Y Bao… - The Journal of …, 2010 - ncbi.nlm.nih.gov
Abstract Zinc-α2-glycoprotein (ZAG, also listed as AZGP1 in the MGI Database), a lipid-
mobilising factor, has recently been suggested as a potential candidate in the modulation of …

Studies on the antiobesity effect of zinc-α2-glycoprotein in the ob/ob mouse

ST Russell, MJ Tisdale - International Journal of Obesity, 2011 - nature.com
Objective: To investigate the mechanism of the lipid depletion by zinc-α 2-glycoprotein
(ZAG). Design: Studies were conducted in the ob/ob mouse, or on isolated adipocytes from …

Zinc-α2-glycoprotein is associated with obesity in Chinese people and HFD-induced obese mice

M Liu, H Zhu, Y Dai, H Pan, N Li, L Wang… - Frontiers in …, 2018 - frontiersin.org
Zinc-α2-glycoprotein (ZAG) plays an important role in the regulation of body weight, body fat,
and glucose metabolism. In this study, we first measured ZAG levels in serum and ZAG …