[HTML][HTML] WHO is recommending against the use of COVID-19 convalescent plasma in immunocompromised patients?

M Franchini, A Casadevall, MJ Joyner, D Focosi - Life, 2023 - mdpi.com
Since December 2019, SARS-CoV-2 is ravaging the globe, currently accounting for over
660 million infected people and more than 6.6 million deaths. As convalescent plasma had …

[HTML][HTML] The assessment of convalescent plasma efficacy against COVID-19

A Casadevall, BJ Grossman, JP Henderson, MJ Joyner… - Med, 2020 - cell.com
Antibody-based therapy for infectious diseases predates modern antibiotics and, in the
absence of other therapeutic options, was deployed early in the SARS-CoV-2 pandemic …

Convalescent plasma therapy in COVID-19: Unravelling the data using the principles of antibody therapy

A Casadevall, MJ Joyner, LA Pirofski… - Expert review of …, 2023 - Taylor & Francis
Introduction When the COVID-19 pandemic struck no specific therapies were available and
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …

COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic review and meta-analysis

JW Senefeld, M Franchini, C Mengoli… - JAMA Network …, 2023 - jamanetwork.com
Importance Patients who are immunocompromised have increased risk for morbidity and
mortality associated with coronavirus disease 2019 (COVID-19) because they less …

[HTML][HTML] COVID‐19 convalescent plasma therapy: hit fast, hit hard!

D Focosi, M Franchini - Vox sanguinis, 2021 - ncbi.nlm.nih.gov
COVID-19 convalescent plasma (CCP) is an investigational treatment for SARS-CoV-2
infection. Several lines of evidence, ranging from expanded access programmes (EAP) to …

Outcomes of convalescent plasma with defined high versus lower neutralizing antibody titers against SARS-CoV-2 among hospitalized patients: CoronaVirus …

LA Bartelt, AJ Markmann, B Nelson, J Keys, H Root… - MBio, 2022 - Am Soc Microbiol
ABSTRACT COVID-19 convalescent plasma (CCP) was an early and widely adopted
putative therapy for severe COVID-19. Results from randomized control trials and …

[HTML][HTML] Prevention and treatment of COVID-19 by mono-and poly-clonal antibodies

D McIntosh, T Burnouf, M Karbiener, MR Farcet… - Blood …, 2023 - ncbi.nlm.nih.gov
The potential for antibody-based COVID-19 treatments received significant attention early
during the pandemic. As COVID-19 vaccines have been developed, approved and …

[HTML][HTML] Evaluation of a COVID-19 convalescent plasma program at a US academic medical center

HB Root, M Gilleskie, CH Lu, A Gilmore, M Evans… - Plos one, 2022 - journals.plos.org
Amidst the therapeutic void at the onset of the COVID-19 pandemic, a critical mass of
scientific and clinical interest coalesced around COVID-19 convalescent plasma (CCP). To …

COVID-19 convalescent plasma

AAR Tobian, CS Cohn, BH Shaz - Blood, The Journal of the …, 2022 - ashpublications.org
As the coronavirus disease (COVID-19) pandemic led to a global health crisis, there were
limited treatment options and no prophylactic therapies for those exposed to severe acute …

COVID-19 convalescent plasma and clinical trials: understanding conflicting outcomes

D Focosi, M Franchini, L Pirofski… - Clinical microbiology …, 2022 - Am Soc Microbiol
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …