The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …

Prefrontal cortex (PFC) mediates an assortment of cognitive functions including working
memory, behavioral flexibility, attention, and future planning. Unlike the hippocampus …

The hippocampus-prefrontal cortex (HPC-PFC) pathway plays a fundamental role in
executive and emotional functions. Neurophysiological studies have begun to unveil the …

Highlights•Chronic stress causes atrophy and decreased connectivity of excitatory neurons
in PFC.•Stress causes disruption of GABAergic inhibitory neurons in the PFC.•GABA …

Serotonergic neurotransmission in prefrontal cortex (PFC) plays a key role in regulating
emotion and cognition under normal and pathological conditios. Increasing evidence …

While the hippocampal formation and the prefrontal cortex each have a well-established role
in cognitive and mnemonic processes, the extent and manner in which these structures …

A brain network comprising the medial prefrontal cortex (mPFC) and amygdala plays
important roles in developmentally regulated cognitive and emotional processes. However …

The hippocampus and prefrontal cortex (PFC) have long been known to play a central role
in various behavioral and cognitive functions. More recently, electrophysiological and …

Dysfunction of the prefrontal cortex (PFC) is a central feature of many psychiatric disorders,
such as attention deficit hyperactivity disorder (ADHD), posttraumatic stress disorder (PTSD) …

OBJECTIVE: This article aims to review basic and clinical studies outlining the roles of
prefrontal cortical (PFC) networks in the behavior and cognitive functions that are …