Protective Effects of Gynostemma pentaphyllum (var. Ginpent) against Lipopolysaccharide-Induced Inflammation and Motor Alteration in Mice

A Mastinu, SA Bonini, M Premoli, G Maccarinelli… - Molecules, 2021 - mdpi.com
Gynostemma pentaphyllum (var. Ginpent)(GP) is a variety of Cucurbit with anti-inflammatory
and antioxidant effects in patients. In this manuscript, the main components present in the …

Gypenoside XVII, an active ingredient from gynostemma pentaphyllum, inhibits C3aR-associated synaptic pruning in stressed mice

MM Zhang, GM Huo, J Cheng, QP Zhang, NZ Li… - Nutrients, 2022 - mdpi.com
Gynostemma pentaphyllum is a herbal medicine widely used in Asian countries, and its
saponin extracts have been shown to possess potent anti-inflammatory effects. Gypenoside …

Ameliorating effects of gypenosides on chronic stress-induced anxiety disorders in mice

TT Zhao, KS Shin, HS Choi, MK Lee - BMC Complementary and …, 2015 - Springer
Abstract Background Ethanol extract from Gynostemma pentaphyllum (GP) shows anti-
stress and anxiolytic functions in mice, and also protects dopamine neurons in 6 …

Curculigoside exerts significant anti‑arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF‑κB signaling pathway

S Tan, J Xu, A Lai, R Cui, R Bai… - Molecular …, 2019 - spandidos-publications.com
The present study aimed to investigate the anti‑arthritic effects of curculigoside isolated from
the rhizome of Curculigo orchioides Gaertn in vivo and in vitro, as well as to determine the …

In in vivo evaluation of the anti-inflammatory and analgesic activities of compound Muniziqi granule in experimental animal models

J Cheng, T Ma, W Liu, H Wang, J Jiang, Y Wei… - … and alternative medicine, 2015 - Springer
Abstract Background Compound Muniziqi granule (MNZQ), a traditional Uighur medicinal
preparation, comprises 13 species of medicinal plants. MNZQ is traditionally used for …

Anti-inflammatory and antioxidant potential of Guaianolide isolated from Cyathocline purpurea: Role of COX-2 inhibition

UU Tambewagh, AD Kandhare, VS Honmore… - International …, 2017 - Elsevier
Background Inflammation activated by oxidative stress can cause various diseases, such as
asthma, rheumatoid arthritis, cancer, diabetes, etc. Plant constituents with sesquiterpene …

Anti‐inflammatory and analgesic activities of cupressuflavone from Cupressus macrocarpa: Impact on pro‐inflammatory mediators

E Al‐Sayed, HA Gad, M El‐Shazly… - Drug Development …, 2018 - Wiley Online Library
Abstract Hit, Lead & Candidate Discovery Inflammation is a complex biological process that
is generally occurs in response to pathological triggers. Both neurodegenerative diseases …

Medicinal value and potential therapeutic mechanisms of Gynostemma pentaphyllum (Thunb.) Makino and its derivatives: An overview

K Li, C Ma, H Li, S Dev, JF He… - Current topics in medicinal …, 2019 - ingentaconnect.com
Gynostemma pentaphyllum (Thunb.) Makino (GpM) and its derivatives, especially
gypenosides (Gyps), are widely used as safe and convenient natural herbal drugs for the …

Antioxidant, anti-rheumatic and anti-inflammatory investigation of extract and dicentrinone from Duguetia furfuracea (A. St.-Hil.) Benth. & Hook. f.

RC do Santos, AV de Souza, M Andrade-Silva… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance The preparations of teas and syrups using Duguetia
furfuracea have been used in folk medicine to treat rheumatism and back pain. Several …

Determination of Therapeutic and Safety Effects of Zygophyllum coccineum Extract in Induced Inflammation in Rats

M Yosri, MM Elaasser, MM Abdel-Aziz… - BioMed Research …, 2022 - Wiley Online Library
Background. Z. coccineum is a facultative plant with many medicinal applications. This study
examined the anti‐inflammatory activity of Zygophyllum coccineum (Z. coccineum) in an …