A Mendelian randomization study of testosterone and cognition in men

JV Zhao, TH Lam, C Jiang, SS Cherny, B Liu… - Scientific Reports, 2016 - nature.com
Testosterone replacement for older men is increasingly common, with some observations
suggesting a protective effect on cognitive function. We examined the association of …

[HTML][HTML] Low serum testosterone concentrations are associated with poor cognitive performance in older men but not women

X Dong, H Jiang, S Li, D Zhang - Frontiers in aging neuroscience, 2021 - frontiersin.org
OBJECTIVE: Current evidence on the association between serum testosterone and
cognitive performance has been inconsistent, especially in older adults. To investigate the …

Testosterone levels and cognition in elderly men: a review

J Holland, S Bandelow, E Hogervorst - Maturitas, 2011 - Elsevier
Average testosterone levels and many cognitive functions show a decline with age. There is
evidence to suggest that this association is not just age related. Results from cell culture and …

Causal effects of serum testosterone levels on brain volume: A sex-stratified Mendelian randomization study

PP Niu, X Wang, YM Xu - Journal of Endocrinological Investigation, 2023 - Springer
Purpose To assess the causal effects of serum testosterone and sex hormone-binding
globulin levels on brain volumetric measurements in women and men. Methods We …

Thinking with your gonads: testosterone and cognition

JS Janowsky - Trends in cognitive sciences, 2006 - cell.com
Sex hormones play a crucial role during brain development, but do they modulate or
maintain cognition throughout life? Despite several million prescriptions annually for …

The effects of testosterone on cognition in elderly men: a review

MF Warren, MJ Serby, DM Roane - CNS spectrums, 2008 - cambridge.org
In this article, the literature examining the relationship between testosterone and various
cognitive domains in elderly men is reviewed. The review focuses on the role of …

The association between endogenous free testosterone and cognitive performance: a population-based study in 35 to 90 year-oldmen and women

PP Thilers, SWS MacDonald, A Herlitz - Psychoneuroendocrinology, 2006 - Elsevier
The relationship between testosterone (T) and cognition has yielded conflicting evidence,
showing both positive and negative influences of T on cognitive performance. The …

Higher serum free testosterone is associated with better cognitive function in older men, while total testosterone is not. The Health In Men Study

BB Yeap, OP Almeida, Z Hyde, SAP Chubb… - Clinical …, 2008 - Wiley Online Library
Objective To determine the relationship of total and free serum testosterone to cognitive
performance in older men. Design Cross‐sectional study of a population‐based sample …

Testosterone and cognitive function: current clinical evidence of a relationship

O Beauchet - European journal of endocrinology, 2006 - academic.oup.com
Background Testosterone levels decline as men age, as does cognitive function. Whether
there is more than a temporal relationship between testosterone and cognitive function is …

Associations of bioavailable serum testosterone with cognitive function in older men: results from the National Health and Nutrition Examination Survey

P Giannos, K Prokopidis, DD Church… - The Journals of …, 2023 - academic.oup.com
Background Age-associated cognitive decline may be influenced by testosterone status.
However, studies evaluating the impact of bioavailable testosterone, the active, free …