ABSTRACT Natriuretic peptide receptor 3 (NPR3) is a clearance receptor by binding and
internalizing natriuretic peptides (NPs) for ultimate degradation. Patients with cardiac failure …

Myocardial infarction (MI), characterized by ischemia-induced cardiomyocyte apoptosis, is
the leading cause of mortality worldwide. NR4A2, a member of the NR4A orphan nucleus …

Brain Natriuretic Peptide (BNP) supplementation after infarction increases heart function and
decreases heart remodeling. BNP receptors, NPR-A and NPR-B are expressed on adult …

Natriuretic peptide receptor A (NPR-A) is the receptor for atrial natriuretic peptide (ANP) and
brain natriuretic peptide (BNP). NPR-A plays critical physiological and pathophysiological …

Previous studies suggested a beneficial effect of natriuretic peptides in animal models of
cardiovascular disease, but the role of natriuretic peptide receptor C (NPRC) in the …

ABSTRACT NPPA/atrial natriuretic peptide (natriuretic peptide type A) exerts critical
pleiotropic effects in the cardiovascular system, limiting cardiomyocyte hypertrophy and …

Abstract Natriuretic peptide receptor 3 (NPR3), mediates natriuretic peptides degradation,
was reported to act as a tumor suppressor or promoter in some types of cancer. Previous …

Abstract Brain Natriuretic Peptide (BNP) injections in adult “healthy” or infarcted mice led to
increased number of non-myocyte cells (NMCs) expressing the nuclear transcription factor …

Background Cardiomyocyte apoptosis plays a vital role in myocardial ischemia–reperfusion
(MI/R) injury; however, the role of beclin1 (BECN1) remains unclear. This study aimed at …

Abstract Natriuretic peptide receptor 3 (NPR3) is the clearance receptor for the cardiac
natriuretic peptides (NPs). By modulating the level of NPs, NPR3 plays an important role in …