[HTML][HTML] Dysbiosis of gut microbiota is associated with the progression of radiation-induced intestinal injury and is alleviated by oral compound probiotics in mouse …

TS Zhao, LW Xie, S Cai, JY Xu, H Zhou… - Frontiers in cellular …, 2021 - frontiersin.org
The acute radiation-induced intestinal injury (RIII) has raised much concerns and is
influenced by non-cytocidal radiation effects including the perturbations in gut microbiota …

Antibiotic alleviates radiation-induced intestinal injury by remodeling microbiota, reducing inflammation, and inhibiting fibrosis

Z Zhao, W Cheng, W Qu, G Shao, S Liu - ACS omega, 2020 - ACS Publications
Radiation-induced intestinal injury is a common complication of abdominal radiation
therapy. However, the pathological features of radiation-induced intestinal injury and its …

[HTML][HTML] The impact of gut microbiota on radiation-induced enteritis

Y Jian, D Zhang, M Liu, Y Wang, ZX Xu - Frontiers in Cellular and …, 2021 - frontiersin.org
Radiotherapy is an important treatment for abdominal tumors. A critical side effect for this
therapy is enteritis. In this review, we aim to summarize recent findings in radiation enteritis …

Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction

S Gerassy-Vainberg, A Blatt, Y Danin-Poleg… - Gut, 2018 - gut.bmj.com
Objective Radiation proctitis (RP) is a complication of pelvic radiotherapy which affects both
the host and microbiota. Herein we assessed the radiation effect on microbiota and its …

Metformin alleviates irradiation-induced intestinal injury by activation of FXR in intestinal epithelia

JY Yang, MJ Liu, L Lv, JR Guo, KY He… - Frontiers in …, 2022 - frontiersin.org
Abdominal irradiation (IR) destroys the intestinal mucosal barrier, leading to severe
intestinal infection. There is an urgent need to find safe and effective treatments to reduce IR …

Radiation injury and gut microbiota-based treatment

W Wang, B Cui, Y Nie, L Sun, F Zhang - Protein & Cell, 2024 - academic.oup.com
The exposure to either medical sources or accidental radiation can cause varying degrees
of radiation injury (RI). RI is a common disease involving multiple human body parts and• …

Faecal microbiota transplantation protects against radiation‐induced toxicity

M Cui, H Xiao, Y Li, L Zhou, S Zhao, D Luo… - EMBO molecular …, 2017 - embopress.org
Severe radiation exposure may cause acute radiation syndrome, a possibly fatal condition
requiring effective therapy. Gut microbiota can be manipulated to fight against many …

The microbiome and radiation induced-bowel injury: evidence for potential mechanistic role in disease pathogenesis

T Kumagai, F Rahman, AM Smith - Nutrients, 2018 - mdpi.com
Radiotherapy has played a major role in both the curative and palliative treatment of cancer
patients for decades. However, its toxic effect to the surrounding normal healthy tissue …

D-galactose protects the intestine from ionizing radiation-induced injury by altering the gut microbiome

T Zhu, Z Wang, J He, X Zhang, C Zhu… - Journal of Radiation …, 2022 - academic.oup.com
This article aims to investigate the protection of the intestine from ionizing radiation-induced
injury by using D-galactose (D-gal) to alter the gut microbiome. In addition, this observation …

High-throughput 16S rRNA gene sequencing reveals alterations of mouse intestinal microbiota after radiotherapy

YS Kim, J Kim, SJ Park - Anaerobe, 2015 - Elsevier
The mammalian gastrointestinal tract harbors a highly complex microbial community that
comprises hundreds of different types of bacterial cells. The gastrointestinal microbiota plays …