We conduct proteome-wide Mendelian randomization and colocalization analyses to
decipher the associations of blood proteins with the risk of type 2 diabetes and diabetic …

Aims/hypothesis The pathogenesis of type 2 diabetes is not fully understood. We
investigated whether circulating levels of preselected proteins were associated with the …

With an estimated prevalence of 463 million affected, type 2 diabetes represents a major
challenge to health care systems worldwide. Analyzing the plasma proteomes of individuals …

The increasing prevalence of type 2 diabetes poses a major challenge to societies
worldwide. Blood-based factors like serum proteins are in contact with every organ in the …

Background Recent advances in proteomics have shed light to discover serum proteins or
peptides as biomarkers for tracking the progression of diabetes as well as understanding …

OBJECTIVE The plasma proteome preceding diabetes can improve our understanding of
diabetes pathogenesis. RESEARCH DESIGN AND METHODS In 8,923 Atherosclerosis Risk …

Aims The epidemiological association between diabetes and cardiovascular disease is well
established, but the pathophysiological link is complex and multifactorial. We investigated …

Aims/hypothesis This study aimed to elucidate the aetiological role of plasma proteins in
glucose metabolism and type 2 diabetes development. Methods We measured 233 proteins …

Background Few biomarkers of type 2 diabetes mellitus (T2DM) are replicable in the
differentiation of T2DM with different complications. We aimed to identify proteomic …

Type 2 diabetes shows an increasing prevalence in both adults and children. Identification
of biomarkers for both youth and adult-onset type 2 diabetes is crucial for development of …